5. Conclusion:
In conclusion, corticosteroid therapy did not lower the but increased the mortality in COVID-19 patients. The possible reasons for the increase in the mortality might be delay in virus clearance and secondary infection due to initiation of corticosteroid therapy atthe early stage of the infection and at the high dose. There is need to conduct further clinical studies for developmentof the standard guideline to use corticosteroids in COVID-19 with considering factors such as initiation of the therapy with monitoring the virus load, dosage, route of administration and duration of the therapy as well as confounding antibiotics.