5. Conclusion:
In conclusion, corticosteroid therapy did not lower the but increased
the mortality in COVID-19 patients. The possible reasons for the
increase in the mortality might be delay in virus clearance and
secondary infection due to initiation of corticosteroid therapy atthe
early stage of the infection and at the high dose. There is need to
conduct further clinical studies for developmentof the standard
guideline to use corticosteroids in COVID-19 with considering factors
such as initiation of the therapy with monitoring the virus load,
dosage, route of administration and duration of the therapy as well as
confounding antibiotics.