Abbreviation
4-NQO 4-nitroquinoline-1-oxide; 5-aza-Dc, 5-aza-20deoxycytidine; 5-Fu;
5-fluorouracil; ABCG2; ATP-binding cassette super-family G member 2;
AhR, Aryl hydrocarbon receptor; AITC, Allyl isothiocyanate; ALDH,
Aldehyde Dehydrogenase; ALP, Alkaline phosphatase; AMPK; Activation of
metabolic regulator phospho-Kinase; AP-1 Activating protein-1; ATRA,
All-trans retinoic acid; AVOs, Acidic vesicular organelles; Bcl-2,
B-cell lymphoma-2; CDDP, Cisdiamminedichloridoplatinum (II); CDKI,
Cyclin dependent kinase inhibitors; CDKs, Cyclin-dependent kinases; CHK,
Checkpoint kinase; CHOP, CCAAT/enhancer-binding protein Homologous
Protein; c-IAP1, Inhibitors of apoptosis proteins; Col1A1, Collagen type
1A1; CYP1A1, Cytochrome P450 1A1; DMBA, 7,12- dimethylbenz(a)anthracene;
DR5, Death receptor 5; DRSPs, Drug resistant spheres; Dvl-2,
Dishevelled-1; EBNA1, Epstein-Barr virus (EBV) nuclear antigen 1; EBV,
Epstein-Bar virus; EC50s, Effective concentration 50%; EGCG,
Epigallocatechin-3-gallate; EMT, Epithilial-Mesenchymal Transition; EPR,
Enhanced Permiation and Retention; ER, Endoplasmic reticulum; ETs FAD,
Flavin adenine dinucleotide; FAK, Focal adhesion kinase; FasL, Factor
associated suicide ligand; FOXO, Forkhead transcription factor box
protein; GADD45, Growth Arrest and DNA Damage 45; GCLC,
Glutamate-cysteine ligase catalytic subunit; GLUT-1, Glucose
transporter-1; GPx, Glutathione peroxidase; GR, Glutathione reductase;
GSH, Reduced glutathione; GSK-3β, Glycogen synthase kinase-3β; GST,
Glutathione S Transferase; GSTM1, Gluthathione S Transfer Mutant1;
HBPCs, Hamster buccal pouch carcinogenesis; HDACi, Histone Deacetylases
inhibitors; HDAs, Histone deacetylases; HGF, Hepatocyte growth factor;
HIF-1α, Hypoxia inducing factor-1 alpha; HNCTICs, Head and Neck Cancer
Tumor Initiating cells; HNSCC, Head and Neck Squamous cell carcinoma;
HPbCD, 2-Hydroxypropyl-b-cyclodextrin; HPV, Human papillomavirus;
HSP-90, Heat shock protein-90; HSV1, Herpes simplex virus type 1; hTERT,
Human telomerase reverse transcriptase; IC50, Inhibitory concentration
50%; IGFBP-5, Insulin-like growth factor binding protein-5; IKK, IκB
kinase; IL-1β, Interleukin-1β; IL-6, Interleukin-6; iNOS, Nitric oxide
synthetase; IVL, Involucrin; JAK, Janus Kinase; JNKs, c-Jun N-terminal
kinases, LC3II,Light chain 3-II; LOH, loss of heterozygosity; LSCC,
Laryngeal Squamous Cell Carcinoma; MAPK, Mitogen activated protein
kinase; Mcl-1, Myeloid cell leukaemia 1; MDR-1, Multi drug resistance;
MMPs, Matrix Metalloproteinases;; MRP1, Multidrug resistance-associated
protein 1; MTA1, Metastasis-associated gene 1; mTOR, Mammalian target of
rapamycin; MVD, Microvessel density; NAG-1, Nonsteroidal
anti-inflammatory drug-activated gene-1; NARNPs, Naringenin loaded
nanoparticles; NF-κB, Nuclear Factor kappa-B; NLRP3, Nod-like receptor
protein 3; NLRP3, Nucleotide-binding oligomerization domain-like
receptor pyrin domain containing 3; NPC, Nasopharyngeal cancer; NPSCC,
Nasopharyngeal Squamous cell carcinomas; NRF2, Nuclear factor-E 2
-related factor-2; OPL, Oral leukoplakia; OPSCC, Oropharyngeal Squamous
Cell Carcinoma; PAB, PARP, Poly (ADP ribose) polymerase; PDK-1,
3‐phosphoinositide‐dependent protein kinase‐1; PDT, Photodynamic
therapy; PGE-2, ProstaglandinsE-2; PI3KCA, Phosphoinositide-3 kinase
caspase; PKB, Protein kinase B; PTEN, Phosphatase and tensin homolog
deleted on chromosome 10; PTX-LiP, Paclitaxel co-loaded liposome; PUMA,
p53 upregulated modulator of apoptosis; REG, Regenerating gene; ROS,
Reactive Oxygen Species; Sal-B SIRT1, Silent information regulator 1;
SMs, Somatic mutations; SOCS, Suppressor of cytokine signalling; SOD,
Superoxide dismutase; Sp1, Transcription factor specificity protein 1;
SPRP1b, Small proline rich protein; TIMP-2, Tissue inhibitors of
metalloproteinases-2; TNF-R, Tumor necrosis factor receptor; TPA,
1,3-tetradecanoyl phorbolacetate; TRAF1, TNF receptor-associated factor
1; TRAIL-R, TNF-related apoptosis-inducing ligand receptor; TRIB3, uPA,
Urokinase-type plasminogen activator; UPR, Unfolded Protein response;
VEGF, Vascular endothelial growth factor; XIAP, X-linked inhibitor of
apoptosis protein; ZEB1, Zinc finger E-box-binding homeobox 1;