3.1 Bioavailabilty
The medicinal potential of majority of the phytochemicals is limited by their poor water solubility and absorption rate due to their lipophilic nature. Some of phytochemicals have very short half-life so before going to target tissue they are excreted out of body. The concern of bioavailability hinders the progress of phytochemicals in clinical progress. There is hope that some phytochemicals with their carrier-mediated delivery and/or their analogs may finally give the solution for eliminating this deadly HNC disease.