Phytochemicals |
Type |
Compound |
Result |
Reference |
Curcumin |
Clinical |
Curcumin |
Reduced oral premalignant & high-risk
lesions |
(Duarte et al., 2010) |
Genistein |
Pre-clinical |
Cetuximab,genistein |
Inhibit Tumor growth,
apoptosis |
(Park et al., 2010) |
Green Tea |
Clinical |
Erlotinib & GTE |
Decreased oral premalignant
lesions |
(Tsao et al., 2009) |
Guggulsterone |
Pre-clinical |
Guggulsterone, |
Increased potency of
cisplatin, erlotinib & cetuximab. |
(Leeman-Neill et al.,
2009) |
Benzylisothiocyanate |
Pre-clinical |
BITC, cisplatin |
Decrease HNC
cells viability, Induced apoptosis |
(Chen et al., 2013) (Lui et
al., 2003) |
Luteolin |
Pre-clinical |
EGCG & luteolin |
Promoted apoptosis, reduced
growth of xenograft tumors |
(Amin et al., 2010) |
Lycopene |
Clinical |
Lycopene |
reduction in the rate of oral &
pharyngeal cancer (HNC). |
(Leoncini et al., 2015) |
Resveratrol |
Pre-clinical |
Resveratrol |
Induced apoptosis |
(Shrotriya et al., 2015) |