Phytochemicals Type Compound Result Reference
Curcumin Clinical Curcumin Reduced oral premalignant & high-risk lesions (Duarte et al., 2010)
Genistein Pre-clinical Cetuximab,genistein Inhibit Tumor growth, apoptosis (Park et al., 2010)
Green Tea Clinical Erlotinib & GTE Decreased oral premalignant lesions (Tsao et al., 2009)
Guggulsterone Pre-clinical Guggulsterone, Increased potency of cisplatin, erlotinib & cetuximab. (Leeman-Neill et al., 2009)
Benzylisothiocyanate Pre-clinical BITC, cisplatin Decrease HNC cells viability, Induced apoptosis (Chen et al., 2013) (Lui et al., 2003)
Luteolin Pre-clinical EGCG & luteolin Promoted apoptosis, reduced growth of xenograft tumors (Amin et al., 2010)
Lycopene Clinical Lycopene reduction in the rate of oral & pharyngeal cancer (HNC). (Leoncini et al., 2015)
Resveratrol Pre-clinical Resveratrol Induced apoptosis (Shrotriya et al., 2015)