INTRODUCTION
Leukemia is a potentially fatal and life-threatening neoplasm affecting
the hematopoietic system.1 Direct invasion of leukemic
neoplastic cells in the skin layers is named leukemia
cutis.1 Leukemia cutis is seen in various frequencies
in leukemia subtypes, but it is most commonly seen in acute
myelomonocytic leukemia (AML-4) and AML-M5 which have the highest rates
of skin manifestations.2 Approximately, about
2.9%–3.7% of AML cases present with leukemia
cutis.2
We report a case of a 76-year-old man with skin rash who was diagnosed
later with acute myeloid leukemia (AML). The patient presented with
hyperpigmented patches on the face and upper trunk with ocular and oral
mucosal changes upon examination. Further workup revealed patient having
acute myeloid leukemia (AML-M5) and skin biopsy showed infiltration with
myeloblasts.