Enrollment feasibility
Between January 2019 and March 2021, 613 individuals were screened for
eligibility (Figure 1). Nine individuals were ineligible because they
did not meet study criteria, recruitment closed before screening was
done on 204 participants. Of the remaining individuals (n=400), 166
declined to participate and 86 were lost to follow up during the
recruitment process. We enrolled 148 of 400 eligible, screened
individuals (recruitment 37%; 95%CI 32.2%, 41.9%) over a 23-month
period (June 2019-May 2021). Demographic characteristics were overall
similar between enrolled versus unenrolled participants (Table S1).