4. 16- and 32-week CR rate in patients with different metabolic status
We performed post hoc analyses on 16-week and 32-week CR rates in patients with different metabolic status (Table 2). In participants with BMI≥28 kg/m2, LNG-IUS group achieved higher 16-week CR rate (41.7% [5/12]) compared with MA group (0% [0/12]); P=0.037). In patients without insulin resistance, LNG-IUS group also had higher 16-week CR rate (48.6% [18/37]) compared with MA group (25.0% [8/32]; P=0.037; Table 2). No difference was found in 32-week CR rate in patients with different metabolic status among the three groups (Table S2).