P-value showed the difference in total adverse events between different
groups. Chi-square test was used, or Fisher exact test was performed
when expect counts were less than 5.
a Comparison between three groups;
b Comparison between MA group and LNG-IUS group.
c Comparison between MA group and MA+LNG-IUS group.
d Comparison between LNG-IUS group and MA+LNG-IUS
group.
P-value<0.05 was the significant threshold in analysis. Safety
analyses were assessed in patients who received study drugs for more
than 3 months. Eventually, 172 out of 180 patients were included.
Abbreviation: MA, megestrol acetate; LNG-IUS, levonorgestrel-releasing
intrauterine system.