Table 2. CFTR Functional Variants by Ethnic Group in SARP and a General Population.
The minor allele Frequencies (MAF) are provided for confirmed and potentially pathogenic variants found with CFTR sequencing data in SARP. MAF for reference populations provided from the ALFA project in dbGap(https://www.ncbi.nlm.nih.gov/snp/). Definition of abbreviations are as follows: AA=African American, NHW=non-Hispanic white, CF-C=cystic fibrosis causing, VVCC=variants of varying clinical consequences. ACMG LP=American College of Medical Genetics-Likely Pathogenic, SARP-Severe Asthma Research Program.