Table 2. CFTR Functional Variants by Ethnic Group in SARP
and a General Population.
The minor allele Frequencies (MAF) are provided for confirmed and
potentially pathogenic variants found with CFTR sequencing data in SARP.
MAF for reference populations provided from the ALFA project in
dbGap(https://www.ncbi.nlm.nih.gov/snp/). Definition of abbreviations
are as follows: AA=African American, NHW=non-Hispanic white, CF-C=cystic
fibrosis causing, VVCC=variants of varying clinical consequences. ACMG
LP=American College of Medical Genetics-Likely Pathogenic, SARP-Severe
Asthma Research Program.