Study design and population
This prospective, single-center study was conducted in the Second
Xiangya hospital, Hunan, China from December 2020 to May 2021 (known as
COVID-19 post-pandemic). Patients who attended gynecological outpatient
department or were transferred to colposcopy examination, both with
abnormal cytology results of ASCUS, LSIL or atypical squamous cells
cannot exclude high-grade squamous intraepithelial lesion (ASC-H) within
three months were enrolled in our study. The exclusion criteria were
elucidated in Figure1. Informed written consents were obtained from all
the participants. Age, menstruation status, present medical history and
HPV results of each patient were collected. Pathological results were
referred as the golden standard.