What this study adds What is already known about this subject
To date, a number of randomized controlled trials have studied the efficacy and safety of some novel topical drugs.However, compared to traditional available topical therapies, the efficacy, safety and tolerability of these new drugs remain unclear.
A previous NMA have shown no difference between the combination of potent corticosteroid and vitamin D analogue and monotherapy,but some studies have shown that the efficacy of combination is superior to the monotherapy components.