4. Results:
The study population comprised of 102 neonates; mean age 1.5±0.8 days
(Min:1 day, Max:5 days), 65 (63.7%) were age 1 day old at time of echo
and 59 (57.8%) neonates were males. Atrial septal defect vs. patent
foramen ovale were found in 67 neonates (65.7%) (Table 1).
Averaged GLS (%) was -19.9 ± 1.2 while GLS-derived ejection fraction
(%) was 60.0 ± 2.7(Table 2).
Fractional shortening (%) was 34± 3. EF using Biplane Simpsons method
(%) 61.0 ± 3,
A Pearson correlation was used to determine the relationship between LV
EF by biplane Simpson’s method and Left Ventricle EF by strain. There is
a small positive correlation between the LV EF by biplane and LV EF by
strain which was statistically significant (r = 0.294, n =
102, p =0.003). On the other hand, there is a small negative
correlation between the FS and LV EF by strain which shows inconclusive
evidence about the significance of the association between the variables
(r = -0.142, n = 102, p =0.). Apical 4-chamber
strain and 4-chamber strain-derived EF was significantly correlated with
GLS and GLS-derived EF (r = 0.756 , n =102,
p<0.001) and (r = 0.735 , n = 102, p<0.001.)
respectively . Additionally, there is weak but statistically significant
correlation between 4-ch strain-derived EF and biplane Simpson EF (r =
0.204 , n = 102, p=0.039) (Table 3). Comparison of demographic data and
echo variables showed no significant difference between male and female
(Table 4). By using linear regression analysis, there was a small
positive correlation between average EF by biplane method and EF by
strain, which was statistically significant
(R2 = 0.087, p =0.003) (Figure 3)