Plasma circulating cell-freeMYCN gene: a noninvasive and prominent recurrence monitoring indicator of neuroblastoma
Ying Liang1, #, Yan Liu2, #, Pin Zhang1, Mengxin Zhang1, Bang Du1, Weyland Cheng1, Zhidan Yu1, Lifeng Li1, Huanmin Wang1, Guangjun Hou1, Xianwei Zhang1, *, Wancun Zhang1, *
1 Henan Key Laboratory of Children’s Genetics and Metabolic Diseases, Zhengzhou Key Laboratory of Precise Diagnosis and Treatment of Children’s Malignant Tumors, Children’s Hospital Affiliated to Zhengzhou University, Zhengzhou, 450018, China
2 Department of Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
* Correspondence to:
Wancun Zhang, PhD and Xianwei Zhang, PhD, Henan Key Laboratory of Children’s Genetics and Metabolic Diseases, Zhengzhou Key Laboratory of Precise Diagnosis and Treatment of Children’s Malignant Tumors, Children’s Hospital Affiliated to Zhengzhou University, longhu road 33, Tel.: 86-373-63866536, Email: zhangwancun@126.com (Wancun Zhang); zhangxw956658@126.com (Xianwei Zhang);
# These authors contributed equally to this work.
Text word count 4675;
Abstract word count: 248;
Brief running title: Plasma MYCN gene is a recurrence monitoring indicator of neuroblastoma
Key words: Neuroblastoma, MYCN , plasma, relapse, monitor, early
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