Plasma circulating cell-freeMYCN gene: a noninvasive and prominent recurrence monitoring
indicator of neuroblastoma
Ying Liang1, #, Yan Liu2, #, Pin
Zhang1, Mengxin Zhang1, Bang
Du1, Weyland Cheng1, Zhidan
Yu1, Lifeng Li1, Huanmin
Wang1, Guangjun Hou1, Xianwei
Zhang1, *, Wancun Zhang1, *
1 Henan Key Laboratory of Children’s Genetics and
Metabolic Diseases, Zhengzhou Key Laboratory of Precise Diagnosis and
Treatment of Children’s Malignant Tumors, Children’s Hospital Affiliated
to Zhengzhou University, Zhengzhou, 450018, China
2 Department of Medicine, The First Affiliated
Hospital of Zhengzhou University, Zhengzhou, China
* Correspondence to:
Wancun Zhang, PhD and Xianwei Zhang, PhD, Henan Key Laboratory of
Children’s Genetics and Metabolic Diseases, Zhengzhou Key Laboratory of
Precise Diagnosis and Treatment of Children’s Malignant Tumors,
Children’s Hospital Affiliated to Zhengzhou University, longhu road 33,
Tel.: 86-373-63866536, Email: zhangwancun@126.com (Wancun Zhang);
zhangxw956658@126.com (Xianwei Zhang);
# These authors contributed equally to this work.
Text word count 4675;
Abstract word count: 248;
Brief running title: Plasma MYCN gene is a recurrence monitoring
indicator of neuroblastoma
Key words: Neuroblastoma, MYCN , plasma, relapse, monitor, early
Tables: 1
Figures: 4