Figure and table legends
Table 1 Baseline information of participants, a Anova Analysis.
b.Chi-square test. c.Kruskal-wallis analysis.
Figure 1 The reduction in symptom score: (A) The reduction in VAS score
2 weeks after ESS. (B)The reduction in VAS score 1 month after ESS. (C)
The reduction in VAS score 6 months after ESS. (D)The reduction in VAS
score 1 year after ESS. (E) The reduction in SNOT-22 score 2 weeks after
ESS. (F)The reduction in SNOT-22 score 1 month after ESS. (G)The
reduction in SNOT-22 score 6 months after ESS. (H)The reduction in
SNOT-22 score 1 year after ESS. (I) The reduction in L-K score 2 weeks
after ESS. (J)The reduction in L-K score 1 month after ESS. (K)The
reduction in L-K score 6 months after ESS. (L) The reduction in L-K
score 1 year after ESS. ESS, endoscopic sinus surgery.
Figure 2 Endoscopic photographs from one patient for each of the three
groups. Figure(A,F,K)show the preoperative endoscopic condition of nasal
cavity. Figure(B,G,L) show the
postoperative ethmoid sinus cavity 2
weeks after ESS. Figure(C,H,M) show the postoperative ethmoid sinus
cavity 1 month after ESS. Figure(D,I,N) show the postoperative ethmoid
sinus cavity 6 months after ESS. Figure(E,J,O) show the postoperative
ethmoid sinus cavity 1 year after ESS. ESS, endoscopic sinus surgery.
Figure 3 SEM photographs from one patient for each of the three groups.
Figure(A,D,G)show the preoperative nasal mucosa. Figure(B,E,H) show the
postoperative nasal mucosa 2 weeks after ESS. Figure(C,F,I) show the
postoperative nasal mucosa 1 month after ESS. SEM, scanning electron
microscope. ESS, endoscopic sinus surgery.
Figure 4 The mRNA expression of CP110, Foxj1 and Tap73. (A) The CP110
mRNA expression among control group, rh-bFGF nasal-spray and nasal-drop
group before ESS. (B) The CP110 mRNA expression among the three groups 2
weeks after ESS. (C) The CP110 mRNA expression among the three groups 1
month after ESS. (D) The Foxj1 mRNA expression among the three groups
before ESS.(E) The Foxj1 mRNA expression among the three groups 2 weeks
after ESS.(F) The Foxj1 mRNA expression among the three groups 1 month
after ESS. (G) The Tap73 mRNA expression among the three groups before
ESS. (H)The Tap73 mRNA expression among the three groups 2 weeks after
ESS. (I) The Tap73 mRNA expression among the three groups 1 month after
ESS.
Figure 5 The reduction in VAS score, SNOT-22 and L-K score in eCRS of
the three group. (a) The reduction in VAS score 2 weeks after ESS.
(B)The reduction in VAS score 1 month after ESS. (C)The reduction in VAS
score 1 month after ESS. (D)The reduction in VAS score 1 month after
ESS.(E) The reduction in SNOT-22 score 2 weeks after ESS. (F)The
reduction in SNOT-22 score 1 month after ESS. (G)The reduction in
SNOT-22 score 6 months after ESS. (H)The reduction in SNOT-22 score 1
year after ESS. (I)The reduction in L-K score 2 weeks after ESS. (J) The
reduction in L-K score 1 month after ESS. (K)The reduction in L-K score
6 months after ESS. (L)The reduction in L-K score 1 year after ESS.
eCRS, eosinophil chronic rihnosinusitis. ESS, endoscopic sinus surgery.
Figure S1 Consort Flow Diagram: Flow diagram of participants enrolled in
this study. Conventional treatment(antibiotics for 3 days and nasal
corticosteriod and irrigation for 1 month).
Figure S2 The reduction of symptom score (A) The reduction in
obstruction score 2 weeks after ESS. (B)The reduction in obstruction
score 1 month after ESS. (C)The reduction in obstruction score 6 months
after ESS. (D)The reduction in obstruction score 1 year after ESS.
(E)The reduction in rhinorrhea score 2 weeks after ESS. (F)The reduction
in rhinorrhea score 1 month after ESS. (G)The reduction in rhinorrhea
score 6 months after ESS. (H)The reduction in rhinorrhea score 1 year
after ESS.
(I)The reduction in olfactory score 2 weeks after ESS. (J)The reduction
in olfactory score 1 month after ESS. (K) The reduction in olfactory
score 6 months after ESS. (L)The reduction in olfactory score 1 year
after ESS. (M) The reduction in facial pressure score 2 weeks after ESS.
(N)The reduction in facial pressure score 1 month after ESS. (O)The
reduction in facial pressure score 6 months after ESS.(P)The reduction
in facial pressure score 1 year after ESS. (Q)The reduction in headache
score 2 weeks after ESS. (R)The reduction in headache score 1 month
after ESS. (S)The reduction in headache score 6 months after ESS. (T)The
reduction in headache score 1 year after ESS. ESS, endoscopic sinus
surgery. ESS, endoscopic sinus surgery.
Figure S3 The reduction in VAS score, SNOT-22 and L-K score in non-eCRS
of the three group. (a) The reduction in VAS score 2 weeks after ESS.
(B)The reduction in VAS score 1 month after ESS. (C)The reduction in VAS
score 1 month after ESS. (D)The reduction in VAS score 1 month after
ESS.(E) The reduction in SNOT-22 score 2 weeks after ESS. (F)The
reduction in SNOT-22 score 1 month after ESS. (G)The reduction in
SNOT-22 score 6 months after ESS. (H)The reduction in SNOT-22 score 1
year after ESS. (I)The reduction in L-K score 2 weeks after ESS. (J) The
reduction in L-K score 1 month after ESS. (K)The reduction in L-K score
6 months after ESS. (L)The reduction in L-K score 1 year after ESS.
eCRS, eosinophil chronic rihnosinusitis. ESS, endoscopic sinus surgery.