Figure legends
Figure
1: Illustration of the scale-down reactor setup. The inside of the STR
with the probe positions for CFD mixing time simulation (A) and the
whole scale-down setup with corresponding labelling (B) are shown. The
values of the dimensioning can be found in Table S 1.
Figure 2: Comparison of the tracer
mass fraction as a function of time at position MP2 in the PFR. For
constant fluid viscosity of 1 mPa.s (A) and shear rate dependent
viscosity at fermentation end (B).
Figure 3: Overview of the
cultivation results. The biomass concentration (A), the total produced
Fab (B), the intracellular Fab fraction (C) and the extracellular Fab
fraction (D) are shown. Data points represent the average of biological
duplicates. The error bars show the deviations to the average of the
individual experiments. The online data for the pH (E) and DO values (F)
are given as well. In F the DO values for MP2 were at 0% during the
whole cultivation.