2.1. Study Design
This study was reviewed and approved by the ethics committee of Mackay Memorial Hospital, Taipei, Taiwan (22MMHIS361e; 2022/12/08) and was registered in ClinicalTrials.gov (NCT05682989). Informed consent was obtained from all the patients involved. History of POP patients who had voiding difficulties and underwent primary TVM surgery for symptomatic POP ≥ stage II (POP-Q system) from January 2007 to December 2022 in Mackay Memorial Hospital were reviewed. Patients with a history of vesico-/recto-/urethra-vaginal fistula or pelvic radiation, and those who did not complete pre- and post-operative followed-ups were excluded from the analysis. The primary outcome assayed in this study was the bladder compliance; and the secondary outcomes were the compliance-associated parameters including infused volume, voiding threshold, and post-voided residual volume.