2.1. Study Design
This study was reviewed and approved by the ethics committee of Mackay
Memorial Hospital, Taipei, Taiwan (22MMHIS361e; 2022/12/08) and was
registered in ClinicalTrials.gov (NCT05682989). Informed consent was
obtained from all the patients involved. History of POP patients who had
voiding difficulties and underwent primary TVM surgery for symptomatic
POP ≥ stage II (POP-Q system) from January 2007 to December 2022 in
Mackay Memorial Hospital were reviewed. Patients with a history of
vesico-/recto-/urethra-vaginal fistula or pelvic radiation, and those
who did not complete pre- and post-operative followed-ups were excluded
from the analysis. The primary outcome assayed in this study was the
bladder compliance; and the secondary outcomes were the
compliance-associated parameters including infused volume, voiding
threshold, and post-voided residual volume.