3.3 TVM increases compliance of late filling
Notably, in pre-operative PVA, the trajectory markedly deviated to the right and downwards at the late half compared to the early half of the filling stage (Figure 3C PRE), indicating the pre-operative compliance was decreased at late filling stage. The heterogeneity of compliance before TVM was confirmed by that the regression line of the late half of the filling stage (blue C2/2) tilted clockwise compared to that of the early half (green C1/2; Figure 2C PRE). Quite differently, post-operative PVA displayed a relatively stable trajectory without marked deviation that resulted in a fairly constant slope through the entire filling stage (Figure 2D POST). The homogeneity of compliance in the post-operative PVA was confirmed by that the regression lines of the early and late halves of the filling stage (green C1/2 and blue C2/2, respectively) displayed resemble slopes (Figure 2D POST). Summarize data measured pre-operatively showed when compared to the mean compliance of the early half of the filling stage (Figure 3C PRE C1/2) that of the late half (C2/2) was significantly decreased before operation (p<0.01, N=22). In contrast, after TVM, no statistical difference was evidenced between the mean compliance of the early and late filling (Figure 3E POST C1/2 and C2/2, respectively; p>0.05, N=22). Moreover, while it failed to statistically affect C1/2 (p>0.05, N=22), TVM post-operatively increased C2/2 when compared with the pre-operative control (p<0.01, N=22), indicating the increased C2/2 contributed essentially to the TVM-enhanced bladder compliance.