Figure 1: Skin biopsy H&E showed diffuse dermal infiltrate with blast-like cells extending to the hypodermis(A40x and B100x). Bone marrow aspirate (100*10x) showing infiltration with atypical cells with an eccentric nucleus, fine nuclear chromatin, and weakly basophilic, easily visible vacuoles in the cytoplasm, agranular cytoplasm with pseudopods (C/D); Immunohistochemistry tumor cells expressed CD4、CD56、CD31、CD43, CD68, BCL-2(not shown), and CD123 but were negative for myeloperoxidase (MPO), CD3, CD20, TDT, CD34, and EBV-encoded RNA (EBER in situ hybridization, not shown).