4.3.1.4. Chloroquine
Chloroquine falls under the category of aminoquinolines and is a wide-spectrum antiviral drug. It has been used to treat malaria as well as autoimmune disease such as lupus erythematosus, rheumatoid arthritis and is an anti-inflammatory agent . It is seen to mainly inhibit the entry, post entry, and transport phases of the COVID-19 virus . This drug essentially inhibits the binding of S protein to the ACE-2 receptor located on the host cell and hence will inhibit replication of the RNA, the glycosylation of the viral proteins, the assembly of the virus, and finally exocytosis . This drug was given emergency use authorization by the US FDA for the treatment of COVID-19 patients .