The probability of ABO incompatibility
The blood group phenotypes were used to calculate ABO gene frequencies
of 85 590 blood donors. The prevalence of blood group B (31.44%) was
slightly higher than that of blood groups A (29.05%) and O (28.54%),
and the distribution characteristics were B > A
> O > AB in the Affiliated Hospital of Qingdao
University in northern China (Fig. 1).
The probabilities of genes A, B, and O were 0.2253, 0.2409, and 0.5338,
derived from the population frequencies of ABO blood group phenotypes in
the recruited blood donors at the Affiliated Hospital of Qingdao
University (the detailed calculation procedure is shown in Supplementary
Information A).
The probability of a blood group O woman giving birth to an infant who
was non-group-O was predicted to be 13.28% at the Affiliated Hospital
of Qingdao University in northern China (the detailed calculation
procedure shown in Supplementary Information B).