5-Conclusion
The outbreak of COVID-19 caused by the novel virus SARS-CoV-2 started at
the end of December 2019. In less than two months, it has spread in many
countries globally. The rapid spread of SARS-CoV-2 and the unprecedented
nature of COVID-19 have demanded urgency in both basic science and
clinical research, and the scientific community has met that call with
remarkable productivity. Within months, there has been a significant
growth of scientific knowledge that has shed some light on the
immunology of SARS-CoV-2 infections.
It is imperative that immune responses against SARS-CoV-2 and mechanisms
of them-driven pathology are further elucidated to better define
therapeutic strategies for COVID-19. Since SARS-CoV-2 is very similar to
SARS-CoV and MERS-CoV and the symptoms are also similar between
COVID-19, SARS, and MERS, the outbreak of COVID-19 has created a sense
of SARS and MERS recurrence. However, there are some remarkable
differences between these CoVs, which are essential for containing the
epidemic and treating the patients.