3.6 Low EVI1 expression independently predicted poor outcomes
Univariate analysis of RFS and OS in the whole cohort were shown in
Table 2. In addition to EVI1 expression at diagnosis, age <1
or >10 and E2A-PBX1 fusion gene were significantly related
to lower RFS rate. Furthermore, WBC count ≥30×109/L
and E2A-PBX1 fusion gene were significantly related to lower OS rate
(all P <0.05).
Variables with P <0.20 in univariate analysis were
entered into multivariate analysis. As shown in Table 3, low EVI1
expression, age <1 or >10 and E2A-PBX1 fusion
gene were independent adverse prognostic factors for RFS, and low EVI1
expression was the only independent adverse prognostic factor for OS.