Acknowledgements
I would like to express my very great appreciation to Dr. Touraine
Renaud, Head of génétique clinique, chromosomique et moléculaire, CHU
Saint-Etienne, Saint Priez en Jarez, France for his valuable and
constructive suggestions during this research work and for allowing me
to use the department’s instrumentation. Also, I thank patients and
their families for their collaboration
Ethical considerations were followed in agreement with the Declaration
of Helsinki throughout this study and it was approved by the Research
Committee/ Center hospital university, Faculty of medicine, University
of Jean Monnet, Saint Etienne, France.
Consent was given by all the control participants.
Consent was given by the Legally authorized representatives/next of kin
of the Down’s Syndrome participants (vulnerable population).
Conflict of interest: None declared