Figure 4.
Effects of different levels of extracellular potassium concertation on hypoxia-induced changes of transmembrane potentials. Panels A and B: Action potential durations at the level of 20%, 50% and 90% of repolarization (APD20, APD50, and APD90, respectively) at [K+] of 1.3 mM and 5.4 mM, respectively. *-p<0.05. Panels C and D: Representative recordings of action potentials at extracellular [К+] of 1.3 mM and 5.4 mM, respectively. See a shortening of APD at 5.4 mM of [К+] in hypoxia and the absence of hypoxia-induced APD shortening at 1.3 mM [К+].