Fig. 2. a. Overview of the identified differentially expressed lung proteins. b. Pie chart showing the most significant molecular and cellular processes across each hypoxic group using normalized protein fold change values. c . Hierarchical clustergram of identified lung proteins using normalized fold change values. Green is down-regulated and red is up-regulated d . IPA based analysis of the most significant pathways as well their overall directionality based on z-scores (blue: down-regulation; white: neutral; grey: no directionality).