Introduction
In December 2019, COVID-19 infection was first reported as a pneumonia cluster from Wuhan, China, but quickly emerged to many countries worldwide, so that the World Health Organization (WHO) declared the disease as a pandemic in March 2020 (1, 2). This pandemic has taken a heavy toll on the healthcare system across the world (2).
The clinical course of COVID-19 is heterogeneous, but fever, dry cough, interstitial pneumonia, fatigue, headache, and loss of taste and smell are the most frequently described symptoms (3). Severity of clinical presentation also varies, while the majority of patients with COVID-19 have a favorable outcome, some develop severe pneumonia eventually leading to acute respiratory distress syndrome (ARDS) and respiratory failure (4), requiring assisted ventilation in intensive care units in up to 12% of patients (5).
Although much is known about acute manifestations of COVID-19, less has been reported about the evolution of the disease and the development of post-infectious complications. COVID-19 can lead to a wide variety of complications affecting pulmonary, neurological, cardiovascular, rheumatological, dermatological, and many other systems (6). There are reports of several post-infection complications with COVID-19 including reactive arthritis (RA) (7-11). Joint involvement in COVID-19 may occur at different stages of the disease and may be represented by non-specific arthralgia or by acute arthritis, as could happen in other viral diseases (12). We report Two cases of COVID-19 infection that were complicated by post-viral ReA.