Abstract
Joint involvement in COVID-19 may occur at different stages of the disease and maybe represented by non-specific arthralgia or by acute arthritis. We report Two cases of COVID-19 infection that were complicated by post-viral reactive arthritis. Case 1: A 47-year-old male was presented, 20 days after a COVID-19 infection with acute right knee arthritis. On biologic data, erythrocyte sedimentation rate and C-reactive protein were normal, and immunologic data were negative. A joint puncture was performed showing a turbid fluid. Testing for microcrystals was negative, as well as the ​synovial fluid culture. An infectious investigation was conducted, which was negative. The patient’s complaints improved significantly, with analgesics and non-steroidal anti-inflammatory drugs (NSAID). Case 2: A 33-year-old female presented, with acute left knee arthritis evolving for 48 hours, free of fever, after a Covid 19 infection treated 15 days ago. On examination, besides knee arthritis, the osteoarticular examination was normal. A biological inflammatory syndrome was noted in laboratory tests. A yellow fluid with multiple PNN was detected in the joint fluid aspiration, with a negative culture. The patient was treated by analgesics and NSAID. The follow Up was highlighted by the arthritis resolution. Conclusion : Both of our cases are consistent with what has already been reported in the literature confirming the development of Post-COVID arthritis and strengthen the impending necessity of wider studies to identify rheumatologic manifestations in the short- and long-terms after surviving COVID-19.