Inclusion & exclusion criteria
The inclusion criteria were age range of 20-70 years old, ability to understand the process of the study, completion of the consent form, systolic blood pressure (SBP) between 120 and 160 mmHg, or diastolic blood pressure (DBP) between 80 and 100 mmHg. On the other hand, the exclusion criteria were pregnancy or breastfeeding, liver or kidney failure, aortic stenosis, infectious and inflammatory diseases, fever, any intolerable side effects, allergic symptoms, and alcohol consumption.