Objective: To evaluate the maternal, perinatal and neonatal outcomes for pregnant women having tested positive for COVID-19 with the reverse transcription polymerase chain reaction (RT-PCR) technique. Design: Retrospective study. Setting: University‐affiliated hospital. Population: Pregnant women with confirmed COVID-19 infection. Methods: PCR tests were administered to the women presenting with clinical complaints indicative of suspected COVID-19, or admitted to the hospital for obstetric reasons. The present study used clinical records to collect data such as general characteristics, clinical signs and symptoms, laboratory findings and radiological imaging results of the pregnant women, as well as the types of delivery and RT-PCR data of the newborns from the women who gave birth. Main outcome measures: Data related to the courses of pregnancy, maternal symptoms, types of delivery, and neonatal outcomes. Results: 523 pregnant women tested positive for COVID-19 with RT-PCR technique. Of these pregnant women, 411 had asymptomatic while 112 women showed at least one symptom. Of the 523 pregnant women in total, 384 maintained their pregnancies. Eventually, 135 women gave birth. Twelve pregnant women (2.2%) in total were treated in the intensive care unit, and three (0.6%) died with COVID-19. All the newborns tested with the RT-PCR technique. All the test results were negative. Conclusion: The existing data show that pregnant women with COVID-19 infection may need to be admitted to intensive care, and they may even be under a serious risk of maternal morbidity which may result in maternal death. Funding: None

Objective: To compare the laparoscopic enclosed electromechanical morcellation (LEM) with vaginal enclosed scalpel morcellation (VSM) in laparoscopic myomectomy procedures. Design: Prospective randomized interventional clinical study. Setting: Tertiary university hospital. Population or Sample: One hundred eighteen patients who underwent laparoscopic myomectomy. Methods: All myomectomy procedures were performed laparoscopically. After myomectomy, tissue removal was accomplished via either LEM using the previously described in-glove morcellation technique or VSM. In the VSM group, myoma was placed into an endoscopic bag and removed through the vagina via posterior colpotomy after scalpel morcellation. Main Outcome Measures: Primary outcome: tissue removal time. Secondary outcome: rescue analgesia requirement, postoperative Visual Analog Scale (VAS) scores, postoperative 3th month scores of Female Sexual Function Index (FSFI). Results: The median tissue removal time was longer in the LEM group (25 min (Range: 14-55)) than the VSM group (20 min (Range: 6-38) (p=.001). Rescue analgesia requirement was significantly higher in the LEM group than the VSM group (mean rank: 56.92 vs 40.92 doses, respectively; p<.001). There was no significant difference between the groups at postoperative VAS scores. There was no significant difference between preoperative and postoperative 3th month total scores of FSFI and subdomains in the LEM group. Conversely, all subdomains and total scores of FSFI (26.5 (16.7-34.8) vs. 22.7 (15.2-28.7) except pain significantly worsened three months after operation in the VSM group. Conclusion: LEM was associated with a longer tissue removal time and increased postoperative analgesic requirement. On the other hand, VSM was associated with worsened postoperative sexual function from baseline.