Figure 3. Measurement of IL-2 production to determine SARS-CoV-2-specific T cell responses in individuals pre- and post-vaccination.
IL-2 release in response to overnight stimulation with the SARS-CoV-2 peptide pool in unexposed (A) and previously infected (B) individuals pre- and post-vaccination (●=pre-vaccination, ●=1stvaccination, ●=2nd vaccination). Square symbol=Janssen vaccine (A only). Results show arithmetic mean +/-SEM. Dashed line = positivity cut off. (C) ROC curves defining sensitivity and specificity for IL-2. AUC and associated P value are indicated.