Figure 3. Measurement of IL-2 production to determine
SARS-CoV-2-specific T cell responses in individuals pre- and
post-vaccination.
IL-2 release in response to overnight stimulation with the SARS-CoV-2
peptide pool in unexposed (A) and previously infected (B) individuals
pre- and post-vaccination (●=pre-vaccination, ●=1stvaccination, ●=2nd vaccination). Square symbol=Janssen
vaccine (A only). Results show arithmetic mean +/-SEM. Dashed line =
positivity cut off. (C) ROC curves defining sensitivity and specificity
for IL-2. AUC and associated P value are indicated.