Figure 4. Measurement of IFN-γ production to determine
SARS-CoV-2-specific T cell responses in individuals pre- and
post-vaccination.
(A) IFN-γ release in response to overnight stimulation with the
SARS-CoV-2 peptide pool in previously unexposed individuals pre- and
post-vaccination (●=pre-vaccination, ●=1stvaccination, ●=2nd vaccination). Square symbol=Janssen
vaccine (A only). Results show arithmetic mean +/-SEM. Dashed line =
positivity cut off. *p<0.05, **p<0.01, ns = not
significant. (B) ROC curves defining sensitivity and specificity for
IFN-γ. AUC and associated P value are indicated.