Figure Legends
Figure 1. Measurement of cytokine productionto determine SARS-CoV-2-specific T cell responses in naturally infected and non-exposed individuals.
(A) IFN-γ and (B) IL-2 release in response to overnight stimulation with SARS-CoV-2 peptide mega pool in PCR-positive (●), suspected infection (●), and no known history of exposure (●) cohorts. Results show arithmetic mean +/-SEM. Dashed line = positivity cut off. *p<0.05, **p<0.01, ****p<0.0001, ns = not significant.
Figure 2.Diagnostic accuracy for IL-2 and IFN-γ as a readout for the T cell test
Receiver operating characteristic curves defining sensitivity and specificity readouts for IL-2 (n=49) (A) and IFN-γ (n = 59) (B) are shown. Area under the curve (AUC) and associated P value are indicated.