Statistical analysis
Continuous variables are presented as medians and interquartile ranges (IQR) and were compared with the Mann-Whitney U test and Kruskal-Wallis H test (independent groups) or Wilcoxon signed rank test (paired groups). Categorical variables are presented as numbers/percentages and were compared with the χ2 test or Fisher’s exact test. Results of logistic regression are reported as odds ratio (OR) and 95% confidence interval (CI). The survival rate was estimated using the Kaplan–Meier method. Five-year progression-free survival (PFS) and OS were calculated from diagnosis to the date of last follow-up, progression, or death. P-values <0.05 were considered statistically significant. Statistical analyses were performed using SPSS Statistics (v.24; IBM Corp.-USA) and RStudio (v.1.3.1093; RStudio, PBC).
RESULTS