Summary of results
The baseline characteristics of the patients are presented in Table 1. The range of age at OFCs was 80–205 months, which is comparatively higher than all OFC patients (median: 47 months; inter-quartile range: 26–81 months). Among the seven patients, six were male. Asthma is the most common comorbidity in allergic diseases.
Detailed information on the adrenaline therapy is presented in Table 2. All patients presented with severe cardiovascular symptoms, and 6 of 7 patients showed respiratory symptoms. The total number of IM adrenaline injections administered was three to four. All patients were treated with a fluid bolus, and only one patient needed intubation for severe respiratory and cardiovascular symptoms.
The initial administration rate of adrenaline infusion was 0.02–0.04 µg/kg/min. Only two patients required an increase in the rate: 0.03 to 0.06 µg/kg/min, and 0.02 to 0.04 µg/kg/min. All patients stabilized after hospitalization, and intravenous adrenaline infusion was discontinued after roughly 3 hours. None of the patients presented with biphasic reactions.