1 | INTRODUCTION
Early diagnosis and treatment of dyslipidemia are required to prevent
the progression of atherosclerosis. Hypertriglyceridemia has been shown
to increase the risk of atherosclerosis, which can lead to the
development of cardiovascular disease.1 Diabetes
mellitus is frequently associated with dyslipidemia, particularly type
Ⅱb, Ⅲ, or Ⅳ hyperlipidemias, which can promote
hypertriglyceridemia.2, 3
Xanthomas are typical skin lesions associated with dyslipidemia that
occur as accumulations especially in the Achilles and patellar tendons,
extensor tendons of the hands and elbows, eyelids, trunk, and
buttocks.4 These skin lesions have been associated
with marked hypercholesterolemia, which is typically observed in
patients with familial hyperlipidemia type Ⅱa.5
With regard to hypertriglyceridemia, evidence suggests that eruptive
xanthomas were associated with serum triglyceride
levels.6 Considering the availability of studies on
the clinical courses of eruptive xanthoma,7–9clinicians should familiarize themselves with the details of this
condition for correct diagnosis in the early stage.
We herein report on a patient with dyslipidemia complicated with type 2
diabetes mellitus, in whom eruptive xanthoma served as an indicator for
hypertriglyceridemia. After improvement of hypertriglyceridemia through
diet and medical treatment, the color tones of the skin lesions had
changed from red to white, ultimately disappearing after several months.