In this article, a COVID-19 transmission mathematical model
incorporating vaccination and non-pharmaceutical interventions was
formulated and theoretically analysed. Here, the COVID-19 free and
endemic equilibrium points, vaccine reproduction number were computed.
The derived vaccination reproduction number largely depends on vaccine
efficacy for disease eradication to occur. Infection risk is
significantly reduced whenever the vaccine intake is greater than one
dosage. The simulation results indicate that the administered COVID-19
vaccines and non-pharmaceutical interventions have been effective for
the current variants, additional efforts such as a third vaccine booster
shot should be considered and implemented to greatly mitigate the risk
of the emerging variants of the COVID-19 pandemic.