Abandonment of therapy
A total of 31/181 (17%) patients abandoned therapy: 21 during chemotherapy, 8 before radiation therapy, and 2 during radiation therapy. Of the 31, 19 (61%) patients never returned. Of the twelve that returned: 8 returned in relapse or progressive disease. Among these 12, five restarted mStanfordV therapy (chemotherapy and radiation) and one received only radiation. Last status of these 12 returned patients are: 6 expired (4 months to 7 years from diagnosis), 2 abandoned therapy second time (17 and 33 months from diagnosis to last contact), 1 lost to follow-up in CR (5 years from diagnosis to last contact), and 3 alive (8 to 11 years from diagnosis to last contact).