Appendix 1
Dopamine was confirmed with the highest degree of certainty since 4 SRM
transitions were monitored instead of a single transition (Fig. A1).
Each SRM transition denotes a characteristic fragmentation pathway of
the target molecule. We considered a positive finding in the samples
when all four SRMs demonstrated a positive signal in the expected
retention time for dopamine. The control samples did not present any
signal in any of the SRM transitions, denoting non-detectable
concentrations.