REFERENCES
- Marini C, De Santis F, Sacco S, et al. Contribution of Atrial
Fibrillation to Incidence and Outcome of Ischemic Stroke: Results from
a Population-Based Study. Stroke . 2005;36(6):1115-1119.
- Pistoia F, Sacco S, Tiseo C, et al. The Epidemiology of Atrial
Fibrillation and Stroke. Cardiol Clin . 2016;34(2):255-268.
- Dries DL, Exner DV, Gersh BJ, et al. Atrial Fibrillation is Associated
with an Increased Risk for Mortality and Heart Failure Progression in
Patients with Asymptomatic and Symptomatic Left Ventricular Systolic
Dysfunction: A Retrospective Analysis of the SOLVD Trials. Studies of
Left Ventricular Dysfunction. J Am Coll Cardiol .
1998;32(3):695-703.
- Ruddox V, Sandven I, Munkhaugen J, et al. Atrial Fibrillation and the
Risk of Myocardial Infarction, All-Cause Mortality and Heart Failure:
A Systematic Review and Meta-Analysis. Eur J Prev Cardiol .
2017;24(14):1555-1566.
- Turagam MK, Garg J, Whang W, et al. Catheter Ablation of Atrial
Fibrillation in Patients with Heart Failure: A Meta-Analysis of
Randomized Controlled Trials. Ann Intern Med .
2019;170(1):41-50.
- Kuck KH, Furnkranz A, Chun KRJ, et al. Cryoballoon or Radiofrequency
Ablation for Symptomatic Paroxysmal Atrial Fibrillation:
Reintervention, Rehospitalization, and Quality-of-Life Outcomes in the
FIRE AND ICE Trial. Eur Heart J . 2016;37(38):2858-2865.
- Mark DB, Anstrom KJ, Sheng S, et al. Effect of Catheter Ablation vs
Medical Therapy on Quality of Life Among Patients with Atrial
Fibrillation: The CABANA Randomized Clinical Trial. JAMA .
2019;321(13):1275-1285.
- Blomstrom-Lundqvist C, Gizurarson S, Schwieler J, et al. Effect of
Catheter Ablation vs Antiarrhythmic Medication on Quality of Life in
Patients with Atrial Fibrillation: The CAPTAF Randomized Controlled
Trial. JAMA . 2019;321(11):1059-1068.
- Weiner MM, Baron EL, Joshi K, et al. Catheter Versus Surgical Ablation
of Atrial Fibrillation: An Analysis of Outcomes. J Cardiothorac
Vasc Anesth . 2018;32(5):2435-2443.
- Chen C, Zhou X, Zhu M, et al. Catheter Ablation Versus Medical Therapy
for Patients with Persistent Atrial Fibrillation: A Systematic Review
and Meta-Analysis of Evidence from Randomized Controlled Trials.J Interv Card Electrophysiol . 2018;52(1):9-18.
- Inohara T, Shrader P, Pieper K, et al. Association of Atrial
Fibrillation Clinical Phenotypes with Treatment Patterns and Outcomes:
A Multicenter Registry Study. JAMA Cardiol . 2018;3(1):54-63.
- Margulescu AD, Mont L. Persistent Atrial Fibrillation vs Paroxysmal
Atrial Fibrillation: Differences in Management. Expert Rev
Cardiovasc Ther . 2017;15(8):601-618.
- Darrat YH, Shah J, Elayi C-S, et al. Regional Lack of Consistency in
the Management of Atrial Fibrillation (from the RECORD-AF Trial).Am J Cardiol . 2017;119(1):47-51.
- Schnabel RB, Yin X, Gona P, et al. 50 Year Trends in Atrial
Fibrillation Prevalence, Incidence, Risk Factors, and Mortality in the
Framingham Heart Study: A Cohort Study. Lancet .
2015;386(9989):154-162.
- Campbell HM, Wehrens XHT. Genetics of Atrial Fibrillation: An Update.Curr Opin Cardiol . 2018;33(3):304-310.
- Chalazon B, Mol D, Darbar FA, et al. Association of Rare Genetic
Variants and Early-Onset Atrial Fibrillation in Ethnic Minority
Individuals. JAMA Cardiol . 2021;6(7):811-819.
- Roselli C, Rienstra M, Ellinor PT. Genetics of Atrial Fibrillation in
2020: GWAS, Genome Sequencing, Polygenic Risk, and Beyond. Circ
Res. 2020;127(1):21-33.
- Fatkin D, Santiago CF, Huttner IG, et al. Genetics of Atrial
Fibrillation: State of the Art in 2017. Heart Lung Circ .
2017;26(9):894-901.
- January CT, Wann S, Alpert JS, et al. 2014 AHA/ACC/HRS Guideline for
the Management of Patients with Atrial Fibrillation: A Report of the
American College of Cardiology/American Heart Association Task Force
on Practice Guidelines and the Heart Rhythm Society.Circulation . 2014;130(23):e199-e267.
- Darbar D, Herron KJ, Ballew JD, et al. Familial Atrial Fibrillation is
a Genetically Heterogeneous Disorder. J Am Coll Cardiol .
2003;41(12):2185-2192.
- Fox CS, Parise H, D’Agostino RB, et al. Parental Atrial Fibrillation
as a Risk Factor for Atrial Fibrillation in Offspring. JAMA .
2004;291(23):2851-2855.
- Christophersen IE, Ravn LS, Budtz-Joergensen E, et al. Familial
Aggregation of Atrial Fibrillation: A Study in Danish Twins.Circ Arrhythm Electrophysiol . 2009;2(4):378-383.
- Weng LC, Choi SH, Klarin D, et al. Heritability of Atrial
Fibrillation. Circ Cardiovasc Genet . 2017;10(6):e001838.
- Postma AV, van der Meerakker JBA, Mathijssen IB, et al. A
Gain-of-Function TBX5 Mutation is Associated with Atypical Holt-Oram
Syndrome and Paroxysmal Atrial Fibrillation. Circ Res.2008;102(11):1433-1442.
- Gudbjartsson DF, Holm H, Sulem P, et al. A Frameshift Deletion in the
Sarcomere Gene MYL4 Causes Early-Onset Familial Atrial Fibrillation.Eur Heart J . 2017;38(1):27-34.
- Li RG, Xu YJ, Ye WG, et al. Connexin45 (GJC1) Loss-of-Function
Mutation Contributes to Familial Atrial Fibrillation and Conduction
Disease. Heart Rhythm . 2021;18(5):684-693.
- Orr N, Arnaout R, Gula LJ, et al. A Mutation in the Atrial-Specific
Myosin Light Chain Gene (MYL4) Causes Familial Atrial Fibrillation.Nat Commun . 2016;7:11303.
- Das S, Makino S, Melman YF, et al. A Mutation in the S3 Segment of
KCNQ1 Results in Familial Lone Atrial Fibrillation. Heart
Rhythm . 2009;6(8):1146-1153.
- Roselli C, Chaffin MD, Weng LC, et al. Multi-Ethnic Genome-Wide
Association Study for Atrial Fibrillation. Nat Genet .
2018;50(9):1225-1233.
- Olesen MS, Andreasen L, Jabbari J, et a. Very Early-Onset Lone Atrial
Fibrillation Patients Have a High Prevalence of Rare Variants in Genes
Previously Associated with Atrial Fibrillation. Heart Rhythm .
2014;11(2):246-251.
- Dewland TA, Olgin JE, Vittinghoff E, Marcus GM. Incident Atrial
Fibrillation Among Asians, Hispanics, Blacks, and Whites.Circulation . 2013;128(23):2470-2477.
- Magnani JW, Norby FL, Agarwal SK, et al. Racial Differences in Atrial
Fibrillation-Related Cardiovascular Disease and Mortality: The
Atherosclerosis Risk in Communities (ARIC) Study. JAMA Cardiol .
2016;1(4):433-441.
- Marcus GM, Olgin JE, Whooley M, et al. Racial Differences in Atrial
Fibrillation Prevalence and Left Atrial Size. Am J Med .
2010;123(4):e1-7.
- Nielsen JB, Thorolfsdottir RB, Fritsche LG, et al. Biobank-Driven
Genomic Discovery Yields New Insight into Atrial Fibrillation Biology.Nat Genet . 2018;50(9):1234-1239.
- Song K, Nam YJ, Luo X, et al. Heart Repair by Reprogramming
Non-Myocytes with Cardiac Transcription Factors. Nature .
2012;485(7400):599-604.
- Lee JY, Kim TH, Yang PS, et al. Korean Atrial Fibrillation Network
Genome-Wide Association Study for Early-Onset Atrial Fibrillation
Identifies Novel Susceptibility Loci. Eur Heart J .
2017;38(34):2586-2594.
- Low SK, Takahaski A, Ebana Y, et al. Identification of Six New Genetic
Loci Associated with Atrial Fibrillation in the Japanese Population.Nat Genet . 2017;49(6):953-958.
- Chalazan B, Mol D, Sridhar A, et al. Genetic Modulation of Atrial
Fibrillation Risk in Hispanic/Latino Cohort. PLoS One .
2018;13(4):e0194480.
- Christophersen IE, Rienstra M, Roselli C, et al. Large-Scale Analyses
of Common and Rare Variants Identify 12 New Loci Associated with
Atrial Fibrillation. Nat Genet . 2017;49(6):946-952.
- Chu HM, Feng MJ, Li YG, et al. Polymorphisms but Not Mutations of the
KCNQ1 Gene Are Associated with Lone Atrial Fibrillation in the Chinese
Han Population. ScientificWorldJournal . 2013;373454.
- Wang H, Teng Y, Wang K, et al. The M235T Polymorphism in the
Angiotensinogen Gene and Atrial Fibrillation: A Meta-Analysis. J
Renin Angiotensin Aldosterone Syst . 2015;16(3):647-652.
- Ebana Y, Ozaki K, Liu L, et al. Clinical Utility and Functional
Analysis of Variants in Atrial Fibrillation-Associated Locus 4q25.J Cardiol . 2017;70(4):366-373.
- Olesen MS, Holst AG, Jabbari J, et al. Genetic Loci on Chromosomes
4q25, 7p31, and 12p12 Are Associated with Lone Atrial Fibrillation
Before the Age of 40 Years. Can J Cardiol . 2012;28(2):191-195.
- Body SC, Collard CD, Sherman SK, et al. Variation in the 4q25
Chromosomal Locus Predicts Atrial Fibrillation After Coronary Artery
Bypass Graft Surgery. Circ Cardiovasc Genet . 2009;2(5):499-506.
- Ryan AK, Blumberg B, Rodriguez-Esteban C, et al. PITX2 Determines
Left-Right Asymmetry of Internal Organs in Vertebrates. Nature .
1998;394(6693):545-551.
- Bai J, Lu Y, Lo A, et al. PITX2 Upregulation Increases the Risk of
Chronic Atrial Fibrillation in a Dose-Dependent Manner By ModulatingIKs and ICaL - Insights
from Human Atrial Modelling. Ann Transl Med . 2020;8(5):191.
- Lubitz SA, Lunetta KL, Lin H, et al. Novel Genetic Markers Associate
with Atrial Fibrillation Risk in Europeans and Japanese. J Am
Coll Cardiol . 2014;63(12):1200-1210.
- Ritchie MD, Rowan S, Kucera G, et al. Chromosome 4q25 Variants Are
Genetic Modifiers of Rare Ion Channel Mutations Associated with
Familial Atrial Fibrillation. J Am Coll Cardiol .
2012;60(13):1173-1181.
- Yoneda ZT, Anderson KC, Quintana JA, et al. Early-Onset Atrial
Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and
Arrhythmia Genes. JAMA Cardiol . 2021;6(12):1371-1379.
- Savio-Galimberti E, Darbar D. Atrial Fibrillation and SCN5AVariants. Card Electrophysiol Clin . 2014;6(4):741-748.
- Wilde AAM, Amin AS. Clinical Spectrum of SCN5A Mutations: Long QT
Syndrome, Brugada Syndrome, and Cardiomyopathy. JACC Clin
Electrophysiol . 2018;4(5):569-579.
- McNair WP, Ku L, Taylor MRG, et al. SCN5A Mutation Associated
with Dilated Cardiomyopathy, Conduction Disorder, and Arrhythmia.Circulation . 2004;110(15):2163-2167.
- Olson TM, Michels VV, Ballew JD, et al. Sodium Channel Mutations and
Susceptibility to Heart Failure and Atrial Fibrillation. JAMA .
2005;293(4):447-454.
- Darbar D, Kannankeril PJ, Donahue BS, et al. Cardiac Sodium Channel
(SCN5A ) Variants Associated with Atrial Fibrillation.Circulation . 2008;117(15):1927-1935.
- Ilkhanoff L, Arking DE, Lemaitre RN, et al. A Common SCN5A Variant is
Associated with PR Interval and Atrial Fibrillation Among African
Americans. J Cardiovasc Electrophysiol . 2014;25(11):1150-1157.
- Herman DS, Lam L, Taylor MRG, et al. Truncations of Titin Causing
Dilated Cardiomyopathy. N Engl J Med . 2012;366(7):619-628.
- Corden B, Jarman J, Whiffin N, et al. Association of Titin-Truncating
Genetic Variants with Life-Threatening Cardiac Arrhythmias in Patients
with Dilated Cardiomyopathy and Implanted Defibrillators. JAMA
Netw Open . 2019;2(6):e196520.
- Akhtar MM, Lorenzini M, Cicerchia M, et al. Clinical Phenotypes and
Prognosis of Dilated Cardiomyopathy Caused by Truncating Variants in
the TTN Gene. Circ Heart Fail . 2020;13(10):e006832.
- Huang K, Trinder M, Roston TM, et al. The Interplay Between Titin,
Polygenic Risk, and Modifiable Cardiovascular Risk Factors in Atrial
Fibrillation. Can J Cardiol . 2021;37(6):848-856.
- Haggerty CM, Damrauer SM, Levin MG, et al. Genomics-First Evaluation
of Heart Disease Associated with Titin-Truncating Variants.Circulation . 2019;140(1):42-54.
- Ahlberg G, Refsgaard L, Lundegaard PR, et al. Rare Truncating Variants
in the Sarcomeric Protein Titin Associate with Familial and
Early-Onset Atrial Fibrillation. Nat Commun . 2018;9(1):4316.
- Lazarte J, Laksman ZW, Wang J, et al. Enrichment of Loss-of-Function
and Copy Number Variants in Ventricular Cardiomyopathy Genes in ‘Lone’
Atrial Fibrillation. Europace . 2021;23(6):844-850.
- Choi SH, Weng LC, Roselli C, et al. Association Between Titin
Loss-of-Function Variants and Early-Onset Atrial Fibrillation.JAMA . 2018;320(22):2354-2364.
- Andreasen L, Bertelsen L, Ghouse J, et al. Early-Onset Atrial
Fibrillation Patients Show Reduced Left Ventricular Ejection Fraction
and Increased Atrial Fibrosis. Sci Rep . 2020;10:10039.
- Khera AV, Chaffin M, Aragam KG, et al. Genome-Wide Polygenic Risk
Scores for Common Diseases Identify Individuals with Risk Equivalent
to Monogenic Mutations. Nat Genet . 2018;50:1219-1224.
- Mars N, Koskela JT, Ripatti P, et al. Polygenic and Clinical Risk
Scores and Their Impact on Age at Onset and Prediction of
Cardiometabolic Diseases and Common Cancers. Nat Med .
2020;26:549-557.
- Weng LC, Preis SR, Hulme OL, et al. Genetic Predisposition, Clinical
Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation.Circulation . 2018;137(10):1027-1038.
- Choi SH, Jurgens SJ, Weng LC, et al. Monogenic and Polygenic
Contributions to Atrial Fibrillation Risk: Results from a National
Biobank. Circ Res. 2020;126(2):200-209.
- Ackerman MJ, Priori SG, Willems S, et al. HRS/EHRA Expert Consensus
Statement on the State of Genetic Testing for the Channelopathies and
Cardiomyopathies. Heart Rhythm . 2011;8(8):1308-1339.
- Ingles J, Macciocca I, Morales A, Thomson K. Genetic Testing in
Inherited Heart Diseases. Heart Lung Circ . 2020;29(4):505-511.
- Goodyear WR, Dunn K, Caleshu C, et al. Broad Genetic Testing in a
Clinical Setting Uncovers a High Prevalence of Titin Loss-of-Function
Variants in Very Early Onset Atrial Fibrillation. Circ Genom
Precis Med . 2019;12(11):e002713.
- Olesen MS, Yuan L, Liang B, et al. High Prevalence of Long QT
Syndrome-Associated SCN5A Variants in Patients with Early-Onset
Lone Atrial Fibrillation. Circ Cardiovasc Genet .
2012;5(4):450-459.
- Brauch KM, Chen LY, Olson TM. Comprehensive Mutation Scanning ofLMNA in 268 Patients with Lone Atrial Fibrillation. Am J
Cardiol . 2009;103(10):1426-1428.
- Taylor MRG, Fain PR, Sinagra G, et al. Natural History of Dilated
Cardiomyopathy Due to Lamin A/C Gene Mutations. J Am Coll
Caridol . 2003;41(5):771-780.
- Yeung C, Enriquez A, Suarez-Fuster L, Baranchuk A. Atrial Fibrillation
in Patients with Inherited Cardiomyopathies. Europace .
2019;21(1):22-32.
- Olesen MS, Nielsen MW, Haunsø S, Svendsen JH. Atrial Fibrillation: The
Role of Common and Rare Genetic Variants. Eur J Hum Genet .
2014;22(3):297-306.
- Hershberger RE, Givertz MM, Ho CY, et al. Genetic Evaluation of
Cardiomyopathy - A Heart Failure Society of America Practice
Guideline. J Card Fail . 2018;24(5):281-302.
- Chang SH, Kuo CF, Chou IJ, et al. Association of a Family History of
Atrial Fibrillation with Incidence and Outcomes of Atrial
Fibrillation: A Population-Based Family Cohort Study. JAMA
Cardiol . 2017;2(8):863-867.
- Alzahrani Z, Ornelas-Loredo A, Darbar SD, et al. Association Between
Family History and Early-Onset Atrial Fibrillation Across Racial and
Ethnic Groups. JAMA Netw Open . 2018;1(5):e182497.
- Wu Z, Jiang C, Li J, et al. Effect of Family History of Atrial
Fibrillation on Recurrence After Atrial Fibrillation Ablation: A
Report from the Chinese Atrial Fibrillation Registry Study. J
Cardiovasc Electrophysiol . 2021;32(3):678-685.
- Heidarali M, Bakhshandeh H, Fazelifar A, Haghjoo M. Clinical Profile
and Outcome of Familial Versus Non-Familial Atrial Fibrillation.Int J Cardiol . 2020;314:70-74.
- Girolami F, Frisso G, Benelli M, et al. Contemporary Genetic Testing
in Inherited Cardiac Disease: Tools, Ethical Issues, and Clinical
Applications. J Cardiovasc Med . 2018;19(1):1-11.
- Wilson BD, Wasmund SL, Sachse FB, et al. Evidence for a Heritable
Contribution to Atrial Fibrillation Associated with Fibrosis.JACC Clin Electrophysiol . 2019;5(4):493-500.
- Jessurun ER, van Hemel NM, Defauw JA, et al. Results of Maze Surgery
for Lone Paroxysmal Atrial Fibrillation. Circulation .
2000;101(13):1559-1567.
- Weimar T, Schena S, Bailey MS, et al. The Cox-Maze Procedure for Lone
Atrial Fibrillation: A Single-Center Experience Over 2 Decades.Circ Arrhythm Electrophysiol . 2012;5(1):8-14.
- Hindricks G, Potpara T, Dagres N, et al. 2020 ESC Guidelines for the
Diagnosis and Management of Atrial Fibrillation Developed in
Collaboration with the European Association for Cardio-Thoracic
Surgery (EACTS): The Task Force for the Diagnosis and Management of
Atrial Fibrillation of the European Society of Cardiology (ESC)
Developed with the Special Contribution of the European Heart Rhythm
Association (EHRA) of the ESC. Eur Heart J . 2021;42(5):373-498.
- Barrett TW, Self WH, Darbar D, et al. Association of Atrial
Fibrillation Risk Alleles and Response to Acute Rate Control Therapy.Am J Emerg Med . 2016;34(4):735-740.
- Parvez B, Vaglio J, Rowan S, et al. Symptomatic Response to
Antiarrhythmic Drug Therapy is Modulated by a Common Single Nucleotide
Polymorphism in Atrial Fibrillation. J Am Coll Cardiol .
2012;60(6):539-545.
- Wu G, Cheng M, Huang H, et al. A Variant of IL6R is Associated with
the Recurrence of Atrial Fibrillation After Catheter Ablation in a
Chinese Han Population. PLoS One . 2014;9(6):e99623.
- Cao H, Xu W, Chen X, et al. Functional Promoter -1816C>G
Variant of RANKL Predicts Risk and Prognosis of Lone Atrial
Fibrillation. Heart Vessels . 2019;34(1):151-158.
- Choi EK, Park JH, Lee JY, et al. Korean Atrial Fibrillation (AF)
Network: Genetic Variants for AF Do Not Predict Ablation Success.J Am Heart Assoc. 2015;4(8):e002046.
- Park JK, Lee JY, Yang PS, et al. Good Responders to Catheter Ablation
for Long-Standing Persistent Atrial Fibrillation: Clinical and Genetic
Characteristics. J Cardiol . 2017;69(3):584-590.
- Wu H, Xu J, Chen S, et al. Association of SCN10A Polymorphisms
with the Recurrence of Atrial Fibrillation After Catheter Ablation in
a Chinese Han Population. Sci Rep . 2017;7:44003.
- Ueberham L, Bollmann A, Shoemaker MB, et al. Genetic ACE I/D
Polymorphism and Recurrence of Atrial Fibrillation After Catheter
Ablation. Circ Arrhythm Electrophysiol. 2013;6(4):732-737.
- Zhong Y, Tang K, Li H, et al. Rs4968309 in Myosin Light Chain 4 (MYL4)
Associated with Atrial Fibrillation Onset and Predicts Clinical
Outcomes After Catheter Ablation in Atrial Fibrillation Patients
Without Structural Heart Disease. Circ J.2019;83(10):1994-2001.
- Rahm AK, Lugenbiel P, Ochs M, et al. Pulmonary Vein Isolation Treats
Symptomatic AF in a Patient with Lamin A/C Mutation: Case Report and
Review of the Literature. Clin Res Cardiol .
2020;109(8):1070-1075.
- Wong GR, Nalliah CJ, Lee G, et al. Genetic Susceptibility to Atrial
Fibrillation is Associated with Atrial Electrical Remodeling and
Adverse Post-Ablation Outcome. JACC Clin Electrophysiol .
2020;6(12):1509-1521.
- Shoemaker MB, Muhammad R, Parvez B, et al. Common Atrial Fibrillation
Risk Alleles at 4q25 Predict Recurrence After Catheter-Based Atrial
Fibrillation Ablation. Heart Rhythm . 2013;10(3):394-400.
- Zhao LQ, Zhang GB, Wen ZJ, et al. Common Variants Predict Recurrence
After Nonfamilial Atrial Fibrillation Ablation in Chinese Han
Population. Int J Cardiol . 2017;227:360-366.
- Hu Z, Zou D. Genotype-Phenotype Associations in Atrial Fibrillation: A
Meta-Analysis. J Interv Card Electrophysiol .
2019;54(3):283-288.
- Ulus T, Dural M, Mese P, et al. Genetic Variants Associated with
Atrial Fibrillation and Long-Term Recurrence After Catheter Ablation
for Atrial Fibrillation in Turkish Patients. Anatol J Cardiol .
2021;25(2):129-138.
- Shoemaker MB, Bollmann A, Lubitz SA, et al. Common Genetic Variants
and Response to Atrial Fibrillation Ablation. Circ Arrhythm
Electrophysiol . 2015;8(2):296-302.
- Husser D, Adams V, Piorkowski C, et al. Chromosome 4q25 and Atrial
Fibrillation Recurrence After Catheter Ablation. J Am Coll
Cardiol . 2010;55(8):747-753.
- He J, Zhu W, Yu Y, et al. Variant rs2200733 and rs10033464 on
Chromosome 4q25 Are Associated with Increased Risk of Atrial
Fibrillation After Catheter Ablation: Evidence from a Meta-Analysis.Cardiol J . 2018;25(5):628-638.
- Choi JI, Baek YS, Roh SY, et al. Chromosome 4q25 Variants and
Biomarkers of Myocardial Fibrosis in Patients with Atrial
Fibrillation. J Cardiovasc Electrophysiol .
2019;30(10):1904-1913.
- Mohanty S, Hall AW, Mohanty P, et al. Novel Association of Polymorphic
Genetic Variants with Predictors of Outcome of Catheter Ablation in
Atrial Fibrillation: New Directions from a Prospective Study (DECAF).J Interv Card Electrophysiol . 2016;45(1):7-17.
- Piccini JP, Connolly SJ, Abraham WT, et al. A Genotype-Directed
Comparative Effectiveness Trial of Bucindolol and Metoprolol Succinate
for Prevention of Symptomatic Atrial Fibrillation/Atrial Flutter in
Patients with Heart Failure: Rationale and Design of the GENETIC-AF
Trial. Am Heart J . 2018;199:51-58.
- Piccini JP, Dufton C, Carroll IA, et al. Bucindolol Decreases Atrial
Fibrillation Burden in Patients with Heart Failure and theADRB1 Arg389Arg Genotype. Circ Arrhythm Electrophysiol .
2021;14(8):e009591.
- Pison L, Hocini M, Potpara TS, et al. Work-Up and Management of Lone
Atrial Fibrillation: Results of the European Heart Rhythm Association
Survey. Europace . 2014;16(10):1521-1523.
- Kirchhof P, Breithardt G, Bax J, et al. A Roadmap to Improve the
Quality of Atrial Fibrillation Management: Proceedings from the Fifth
Atrial Fibrillation Network/European Heart Rhythm Association
Consensus Conference. Europace . 2016;18(1):37-50.
- Hall JL, Barac A, Benjamin EJ. Genetic Mutations as Risk Predictors of
Atrial Fibrillation Recurrence After Catheter Ablation? J Am
Coll Cardiol . 2010;55(8):754-757.
- Lubitz SA, Parsons OE, Anderson CD, et al. Atrial Fibrillation Genetic
Risk and Ischemic Stroke Mechanisms. Stroke .
2017;48(6):1451-1456.
- Pulit SL, Weng LC, McArdle PF, et al. Atrial Fibrillation Genetic Risk
Differentiates Cardioembolic Stroke from Other Stroke Subtypes.Neurol Genet . 2018;4(6):e293.
- Kumar S, Baldinger SH, Gandjbakhch E, et al. Long-Term Arrhythmic and
Nonarrhythmic Outcomes of Lamin A/C Mutation Carriers. J Am Coll
Cardiol . 2016;68(21):2299-2307.
- Verdonschot JAJ, Hazebroek MR, Karpels IPC, et al. Implications of
Genetic Testing in Dilated Cardiomyopathy. Circ Genom Precis
Med . 2020;13(5):476-487.