Anatomic
variations of the paranasal sinus area in pediatric chronic
rhinosinusitis with nasal polyps
Abstract
objectives:
We aimed to report the prevalence
of anatomic variations in Chinese pediatric patients with chronic
rhinosinusitis with nasal polyps
(CRSwNP) and to explore the
correlation between anatomic variations and the extent of chronic
sinusitis in children.
Design:This
retrospective
study conducted between January 2018 and June 2020.
Setting: This study involved children from the A Hospital
and B Medical Center.
Participants: Participants included 50 children with
CRSwNP.
Main outcome measures: The diagnosis of CRSwNP was based
on symptoms, endoscopy, and computed tomography examination according to
European criteria on chronic rhinosinusitis. The presence of anatomical
variations was determined, and its correlation with disease extension
was analyzed.
Results: Fifty children were included in the study. The
anterior ethmoid sinus was the most commonly affected sinus in children,
followed by the maxillary, posterior ethmoid, frontal, and sphenoid
sinuses. Agger nasi cells were the most common anatomic variation in
children sinus (96%), followed by inferior turbinate hypertrophy
(60%), septal deviation (55.1%), concha bullosa (45.8%), Onodi cells
(44.9%), Haller cells (38%), and paradoxical middle turbinate (4%).
No significant correlation was found between anatomic variation and
corresponding sinusitis hypertrophy and maxillary sinusitis (P> 0.05).
Conclusions: Our
results found no correlation between anatomic variations and sinusitis
in pediatric CRSwNP. The occurrence of pediatric CRSwNP is as attributed
more to immunological, infectious, or other factors rather than anatomic
variations.
Keywords: Anatomic variations, Pediatric, Chronic
rhinosinusitis with nasal polyps (CRSwNP), Computed tomography (CT)