Conclusions:
To our knowledge, this is the first study to look into the association
between DS in mothers and obstetric outcomes. In conclusion, our study
showed that pregnant women with DS have higher risk to of having preterm
delivery and IUFD. In addition, infants born to mothers with are more
likely to be SGA and to have congenital anomalies. Women with DS should
be counseled preconceptionally and prenatally about their increased risk
of premature delivery and adverse neonatal outcomes. Intervention such
as screening for and enrolling in drug or smoking cessation programs
might be beneficial in eliminating some but not all of these adverse
outcomes.