Physiology of reactive oxygen species
ROS are considered to be byproducts of cellular metabolism and normal
physiologic processes. Some studies have shown that normal levels of ROS
for sperm maturation, chemotaxis, acrosome reaction, zona pellucida
binding, hyperactivation, capacitation, and sperm-oocyte fusion are
needed. Additionally, ROS are crucial intermediaries that have some
roles in gene regulation and vascular tone within the testis(12).