Conclusion
It has been reported that in the peritoneal fluid of endometriosis’
patients, there are activated macrophages and growth factors and high
concentrations of cytokines. These conditions have been toxic to embryo
survival and sperm function. ROS can mediate these conditions. Moreover,
it can have some relations with iron concentrations in peritoneal fluid.
Novel therapeutic strategies must regulate intracellular ROS signaling
to inhibit the adverse effects of ROS-induced endometriosis-promoting
events. According to features of antioxidants, they may inhibit early
events of the development of endometriosis.