A (n=55) B (n=55) C (n=90)
p
A vs B
A vs C
B vs C
Age, years 64 (39-78) 57 (50-67) 52 (40-63) 0.017 0.182 <0.01 0.014
Male sex, n 31 (56.4%) 32 (58.2%) 53 (58.9%) 0.956 0.848 0.766 0.933
Comorbidities, n None
Hypertension
COPD/asthma
Overweight/obesity
Active smoking
Diabetes
Cancer
Others
15 (27.3%) 27 (49.1%) 12 (21.8%) 8 (14.5%) 12 (21.8%) 8 (14.5%) 5 (9.1%) 11 (20.0%) 23 (41.8%) 13 (23.6%) 6 (10.9%) 8 (14.5%) 2 (3.6%) 6 (10.9%) 5 (9.1%) 19 (34.5%) 49 (54.4%) 16 (17.8%) 15 (16.7%) 11 (12.2%) 9 (10.0%) 5 (5.6%) 7 (7.8%) 16 (17.8%) <0.01 <0.01 0.306 0.892 0.010 0.186 0.947 0.080 0.110 <0.01 0.124 0.999 <0.01 0.569 0.999 0.164 <0.01 <0.01 0.441 0.689 0.051 0.067 0.781 0.515 0.141 0.394 0.341 0.689 0.162 0.239 0.781 0.028
Time from COVID-19 onset to diagnostic swab, days 3 (2-5) 5 (3-9) 5 (3-10) 0.011 0.012 0.014 0.949
Number of signs and symptoms at diagnosis, n 4 (2-6) 3 (2-4) 3 (2-4) <0.01 0.126 0.038 0.888
Hospital admissions, n 41 (74.5%) 35 (63.6%) 51 (56.7%) 0.096 0.218 0.031 0.409
Worst oxygen support, n None
Low-flow wall oxygen to reservoir
CPAP
Intubation
24 (43.6%) 20 (36.4%) 7 (12.7%) 4 (7.3%) 28 (50.9%) 11 (20.0%) 11 (20.0%) 5 (9.1%) 47 (52.2%) 29 (32.2%) 11 (12.2%) 3 (3.3%)
0.495
0.923
0.280
0.377
Outcomes, n Complete recovery
Sequelae
Death
16 (29.1%) 19 (34.5%) 20 (36.4%) 39 (70.9%) 9 (16.4%) 7 (12.7%) 72 (80.0%) 13 (14.4%) 5 (5.6%)
<0.01
<0.01
<0.01
0.172
Disease severity, n Home isolation
Hospital admission:
without oxygen support
with low-flow/reservoir
with CPAP
with intubation
Death
14 (25.4%) 10 (18.2%) 5 (9.1%) 3 (5.4%) 3 (5.4%) 20 (36.4%) 20 (36.4%) 8 (14.5%) 8 (14.5%) 7 (12.7%) 5 (9.1%) 7 (12.7%) 39 (43.3%) 8 (8.9%) 26 (28.9%) 10 (11.1%) 2 (2.2%) 5 (5.6%)
<0.01
0.055
<0.01
0.176
A (n=35) B (n=48) C (n=85)
p
A vs B
A vs C
B vs C
Outcomes among survivors, n Complete recovery
Sequelae
16 (45.7%) 19 (54.3%) 39 (81.2%) 9 (18.8%) 72 (84.7%) 13 (15.3%)
<0.01
<0.01
<0.01
0.608
Type of Sequelae, n Dyspnoea
O/G dysfunction
Chronic cough
Others
11 (57.9%) 6 (31.6%) 3 (15.8%) 3 (15.8%) 1 (11.1%) 4 (44.4%) 3 (33.3%) 1 (11.1%) 9 (69.2%) 3 (23.1%) 1 (7.7%) 2 (15.4%) 0.022 0.579 0.294 0.945 0.039 0.677 0.352 0.998 0.713 0.704 0.264 0.976 0.011 0.376 0.264 0.999