Copyright © 2024, the authors. 

Introduction

This article is meant to disseminate scientific progress on Gilles de la Tourette Syndrome (GTS) that appeared in the year 2024, summarizing research reports the authors judged important or interesting. 

Methods

We searched PubMed using the search strategy ("Tic Disorders"[MeSH] OR Tourette) NOT ((Tourette[AU] OR Tourette[COIS]) NOT ("Tic Disorders"[MeSH] OR Tourette [tiab])) AND 2024[PDAT] NOT 1800:2023[PDAT]. On 24 Jan 2024 this search returned 14 citations. On the same date, a search of PubMed Central for ("tic disorders"[mesh] OR tourette*[ti] OR tourette*[ab] OR Tourette*[kwd] OR tourettism[tw]) AND 2024[dp] NOT 1800:2023[dp] returned 7 citations. All these citations are available in this NLM article collection. Colleagues also recommended articles, and we attended selected medical conferences. We selected material for this review subjectively, guided by our judgment of possible future impact on the field.

Results

Phenomenology and natural history

Definition and phenomenology

An analysis of a large TS genetics database examined possible sex differences in people with a persistent tic disorder \citep{Dy_Hollins_2024}. Girls were diagnosed later and less often, but symptoms started only slightly later (0.5-1.0 years) and were of similar severity. OCD was more common in females and ADHD was more common in males. The Montreal group examined possible sex differences in 66 children age 7-14 with tics, 19 of whom were girls (doi 10.3390/jcm13092477). They found no differences in tic symptoms, but substantial differences in psychological style, comorbidity and impairment.
Sleep in TS \citep{38101103}.

Assessment and quantification of tics

Important work: "Automatic identification of facial tics using selfie-video" \citep{Loewenstern_2024}.