\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}

\title{Decitabine combined regimen in the therapy of Blastic plasmacytoid
dendritic cell neoplasm: case report}



\author[1]{Jun Guan}%
\author[1]{Ying Zhou}%
\author[2]{xia Mao}%
\author[1]{Liang Zou}%
\author[1]{Hui Cheng}%
\affil[1]{Wuhan No 1 Hospital}%
\affil[2]{Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology}%


\vspace{-1em}



  
  \date{June 15, 2024}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
We enrolled a patient diagnosed with blastic plasmacytoid dendritic cell
neoplasm (BPDCN) . We have found that TET2, KRAS and BRAF may be
involved in the development of the disease, and the combination therapy
of Decitabine (DAC) and Arsenic acid (ASO) may be effective for BPDCN
harboring the TET2 mutations.%
\end{abstract}%



\sloppy


\textbf{Hosted file}

\verb`20211201BPDCN.doc`  available at \url{https://authorea.com/users/450729/articles/549023-decitabine-combined-regimen-in-the-therapy-of-blastic-plasmacytoid-dendritic-cell-neoplasm-case-report}\selectlanguage{english}
\begin{figure}[H]
\begin{center}
\includegraphics[width=0.70\columnwidth]{figures/fig1/fig1}

\end{center}
\end{figure}\selectlanguage{english}
\begin{figure}[H]
\begin{center}
\includegraphics[width=0.70\columnwidth]{figures/FIG2-00/FIG2-00}

\end{center}
\end{figure}

\selectlanguage{english}
\FloatBarrier
\end{document}

