Acknowledgments
P.Q-C acknowledges financial support from Generalitat Valenciana through the research staff-training program (GVA ACIF / 2018/173). P.C. awards grants Ramón y Cajal and PID2019-110630GB-I00 funded by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A way of making Europe”. S.M awards grants PID2019-110713RB-I00 funded by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A way of making Europe”. PROMETEO/2020/094, Proyecto “88/2021” “Nominativa Acción 2021-12. β-DesLac funded by Generalitat Valenciana, FMV-ANII 148245, FMV-ANIII 156321 funded by Agencia Nacional de Investigación and CSIC 2007-348 UdelaR, Uruguay, are also acknowledged..
P. Q-C performed experiments, analyzed the data, wrote and read the manuscript; P.S analyzed the data and read the manuscript; E. I-E and D. H-F collected the patients’ samples and contributed to the clinical investigation of the patients and read the manuscript; P. C designed and supervised the experiments and read the manuscript; S. M designed and supervised experiments, analyzed the data, wrote and read the manuscript; G. L and G. G-S supervised the experiments and read the manuscript; Á. M supervised experiments and read the manuscript.