Figure 3 |The top sequence features for predicting guide RNA
activities
(a)The features for adjacent dimers of guide RNAs are plotted as
heatmaps based on their position in seed region, and positive
coefficients suggest positive contributions to guide RNA activity.
(b)The features for adjacent trimers of guide RNAs are plotted as
heatmaps based on their position in seed region, and positive
coefficients suggest positive contributions to guide RNA activity.
(c) The features for adjacent nucleotides of guide RNAs are plotted as
columns based on their position in seed region, and positive
coefficients suggest positive contributions to guide RNA activity.
(d) T7EI analysis of targeted indel frequencies induced by the 6 guide
RNAs with different sequence features.