2.1 Materials
The cancer growth-inhibiting (CGI) siRNA and other siRNAs were synthesized by Genolution Pharmaceuticals Inc. (Table S1). (Seoul, Korea). The Cy3-labeled siRNA was synthesized by GenePharma Co., Ltd. (Shanghai, China). The FITC-labeled siRNA was synthesized by Bioneer Co. (Daejeon, South Korea). R11 single peptide and RS and RT fusion peptides in Table S2 were synthesized by GL Biochem, Ltd. (Shanghai, China) with more than 95% purity. Dulbecco’s phosphate-buffered saline (DPBS) and heparin sodium salt (from porcine intestinal mucosa) were purchased from Sigma–Aldrich (MO, USA). Agarose was purchased from Becton Dickinson and Company (Cockeysville, MD). 10,000× TopRed Nucleic Acid Gel Stain was purchased from GenomicBase (Seoul, South Korea). Tris(hydroxymethyl) aminomethane (Tris) was purchased from Glentham Life Sciences Ltd. (Corsham, UK). Acetic acid (glacial) was purchased from Merck (Darmstadt, Germany). 6× DNA loading dye was procured from Biofact Co., Ltd. (Daejeon, South Korea). For cell cultures, Dulbecco’s modified eagle’s medium (DMEM; Corning, MA, USA), fetal bovine serum (FBS; PAN Biotech, Bavaria, Germany), and penicillin-streptomycin (Life Technologies, CA, USA) were procured. Opti-MEM™ and 0.25% trypsin-EDTA (1×) were purchased from Thermo Fisher Scientific, Inc. (MA, USA). Hoechst 33342 was purchased from Invitrogen, Inc. (CA, USA). Phalloidin was procured from BioActs, Inc. (Incheon, South Korea). Nuclease-free water (NFW) was purchased from Integrated DNA Technologies, Inc (IA, USA). All cell culture flasks and plates were purchased from NEST Biotechnology Co., Ltd (Wuxi, China). CCK cell viability assay kit was procured from Donginbio, Inc. (Seoul, Korea). Tri-RNA solution was purchased from Biotech Co. (Kaohsiung, Taiwan)