Introduction
Transient global amnesia (TGA) is characterized by a sudden, complete inability to retain new information, lasting for several hours, with preservation of alertness and all other cognitive functions. During a TGA episode, anterograde amnesia occurs characteristically, with an inability to retain new information for more than a few seconds, and retrograde amnesia extends backward for several hours, days, or longer.[1] Takotsubo syndrome (TTS) is characterized by acute transient left ventricular systolic dysfunction, not explained by coronary artery disease, which has to be distinguished from acute myocardial infarction.[2] Emotional and physical stressors play a role as triggers for TGA and TTS, and coincidence of both conditions has been reported (Table).[3][4][5][6][7][8][9][10][11][12][13][14] In a cross-sectional study of US hospitalizations, from 2006 to 2014, there were 155,105 diagnoses of TTS. TTS was associated with TGA with an odds ratio of 2.3 (95% confidence interval 1.5-3.6).[15] In most cases, the trigger lasted only for a short period of time (Table). We report a case of simultaneous TGA and TTS triggered by a long-term stressful condition.