loading page

Feasibility and safety of left atrial posterior wall isolation with a new Cryoballoon technology in patients with persistent atrial fibrillation
  • +15
  • Antonio Bisignani,
  • Luigi Pannone,
  • Vincenzo Miraglia,
  • Juan Sieira,
  • Saverio Iacopino,
  • Gezim Bala,
  • Erwin Stroker,
  • Ingrid Overeinder,
  • Alexandre Almorad,
  • Anaïs Gauthey,
  • Cinzia Monaco,
  • Gaetano Paparella ,
  • Thiago Guimarães Osório,
  • Antonio Sorgente,
  • Luc Jordaens,
  • Pedro Brugada,
  • Gian battista Chierchia,
  • Carlo de Asmundis
Antonio Bisignani
Policlinico Universitario Agostino Gemelli
Author Profile
Luigi Pannone
IRCCS Ospedale San Raffaele
Author Profile
Vincenzo Miraglia
Vrije Universiteit Brussel
Author Profile
Juan Sieira
UZ Brussel
Author Profile
Saverio Iacopino
Villa Maria Cecilia
Author Profile
Gezim Bala
Vrije Universiteit Brussel
Author Profile
Erwin Stroker
Universitair Ziekenhuis Brussel
Author Profile
Ingrid Overeinder
UZ Brussel, Vrije Universiteit Brussel
Author Profile
Alexandre Almorad
Vrije Universiteit Brussel
Author Profile
Anaïs Gauthey
Vrije Universiteit Brussel
Author Profile
Cinzia Monaco
Vrije Universiteit Brussel
Author Profile
Gaetano Paparella
Heart Rhythm Management Center, Cardiovascular Center UZ Brussel Vrij Universiteit Brussel, Dpt Cardiology laarbeeklaan 101 Brussel, Jette, BE 1090 0032-2-4763038, Cardiology Brussels, BE 0032-2-4763038
Author Profile
Thiago Guimarães Osório
Heart Rhythm Management Center, Cardiovascular Center UZ Brussel Vrij Universiteit Brussel, Dpt Cardiology laarbeeklaan 101 Brussel, Jette, BE 1090 0032-2-4763038, Cardiology Brussels, BE 0032-2-4763038
Author Profile
Antonio Sorgente
Cleveland Clinic Abu Dhabi
Author Profile
Luc Jordaens
Erasmus MC
Author Profile
Pedro Brugada
Free University of Brussels
Author Profile
Gian battista Chierchia
heart rhythm management center
Author Profile
Carlo de Asmundis
UZ Brussel-VUB
Author Profile

Abstract

Introduction: Left atrial posterior wall isolation (LAPWI) is often performed in addition to pulmonary vein isolation (PVI) to improve outcome in patients with persistent atrial fibrillation (AF). In this setting, LAPWI + PVI using cryoballoon ablation had comparable results with radiofrequency ablation (RFA). The aim of the study is to evaluate the feasibility and safety of a new cryoballoon ablation system in PVI + LAPWI isolation, comparing it with the historical platform. Methods: The study was a prospective, non-randomized, single center study. Forty consecutive patients, undergoing PVI + LAPWI with the novel POLARx™, were compared to 40 consecutive patients who underwent the same procedure with the established Arctic Front Advance PRO™. Results: Acute isolation was achieved in all PVs in both groups and LAPWI was achieved in 38 patients (95%) in the POLARx group and in 36 patients (90%) in Arctic Front group. Procedural outcomes were similar between the two groups, except for lower temperatures during cryoapplications in the POLARx group, for both PVI and LAPWI. The complication rate was low and similar between groups. Conclusion: LAPWI+PVI with the novel POLARx™ Cryoballoon is feasible and safe; the results are comparable with the Arctic Front Advance PRO™ system.
07 Apr 2022Published in Pacing and Clinical Electrophysiology. 10.1111/pace.14495