Patient characteristics
A total of 2342 patients underwent surgical repair for TAAAD. Of these,
363 (15.5%) presented with CM. 100 (27.5%) were females, and the mean
age was 65.7±13 years [3,5, 8, 9, 12-19]. All patients were
confirmed TAAAD with CM by clinical presentation and contrast-enhanced
CT or carotid duplex scan, and received surgical repair for TAAAD. No
studies reported the preoperative EuroSCORE II or the American Society
of Anesthesiologists score.
In ‐hospital mortality, cause of death and follow-up
In-hospital mortality was 20.1% (n = 73), ranging from 0 to 50%. 10
studies (n = 222 ) documented the causes of death: severe brain damage
or neurological (n = 28/222), multiorgan failure (n = 1/222), aortic
rupture (n = 1/222), acute myocardial infarction (n = 1/222), and small
bowel necrosis (n = 1/222). The median time from onset of neurological
symptoms to surgery was 13.3 ± 31.3 (range, 0.6 - 240) hours. Of these,
214 cases were within 10h, and 149 cases were >10h. The
mortality was 16.7% and 23.4% respectively. Mean duration of follow-up
was 40.1 ± 37.6 months in 10 papers for 302 patients. Of these studies,
the five-year survival was 65.3% ± 11% in 5 papers, and the 10-year
survival was 60.5 ± 23.4% and 59% ± 9% respectively in two studies.