Patient characteristics
A total of 2342 patients underwent surgical repair for TAAAD. Of these, 363 (15.5%) presented with CM. 100 (27.5%) were females, and the mean age was 65.7±13 years [3,5, 8, 9, 12-19]. All patients were confirmed TAAAD with CM by clinical presentation and contrast-enhanced CT or carotid duplex scan, and received surgical repair for TAAAD. No studies reported the preoperative EuroSCORE II or the American Society of Anesthesiologists score.
Inhospital mortality, cause of death and follow-up
In-hospital mortality was 20.1% (n = 73), ranging from 0 to 50%. 10 studies (n = 222 ) documented the causes of death: severe brain damage or neurological (n = 28/222), multiorgan failure (n = 1/222), aortic rupture (n = 1/222), acute myocardial infarction (n = 1/222), and small bowel necrosis (n = 1/222). The median time from onset of neurological symptoms to surgery was 13.3 ± 31.3 (range, 0.6 - 240) hours. Of these, 214 cases were within 10h, and 149 cases were >10h. The mortality was 16.7% and 23.4% respectively. Mean duration of follow-up was 40.1 ± 37.6 months in 10 papers for 302 patients. Of these studies, the five-year survival was 65.3% ± 11% in 5 papers, and the 10-year survival was 60.5 ± 23.4% and 59% ± 9% respectively in two studies.