Conclusion
This retrospective cohort study adds new evidence to the significant and
frequent complications of treatment in NOE. Identification of the
commonly occurring issues and the potential impact this will have on
antibiotic regimes, allows clinicians to counsel patients appropriately
when initiating treatment. It can also increase awareness and inform
appropriate monitoring for adverse events. Further data may help
identify which patients may be more susceptible to these adverse effects
and managed appropriately.