The digital light projector (DLP) module is fixed on the sample stage, and thus is unaffected by any adjustment in z-plane focus. It is instead focused independently using a screw lever attached to the projector. Light from the projector is focused by a condenser lens (50 mm diameter PCX condenser lens, Edmund Optics), resulting in a total projection size of 14.5 × 26 mm. A white LED (RS Components) can also be attached behind the condenser lens to act as a bright-field light for standard microscopy. To provide an illumination across the sample, a ground glass diffuser (Thor Labs) is placed between the LED and condenser lens. It is additionally possible to attach an LED at an offset angle as shown in Figure \ref{544078} to provide illumination for fluorescence imaging. Although this functionality was not used in this work, an LED aligned with the excitation peak of a given fluorescent molecule can be used in conjunction with wavelength specific filters to allow for more detailed imaging of samples such as bacteria or mammalian cells.  Note that although the DOME is capable of both fluorescence and bright-field illumination, these features were not used in the work presented here as the projector itself was used as the sole light source. A camera (Camera Module V2, Raspberry Pi) sits on the base of the imaging column and is pointed upwards towards the sample stage. Optics such as wavelength or neutral density filters can be added into the optics holder within the imaging column on an application specific basis. For the lower magnification configuration, the imaging column ends with a 9X tube lens (Eyepiece Cell Assembly, Edmund Optics) screwed into a threaded cylindrical casing. For higher magnification applications the cylindrical section is extended, ending in an RMS thread to fit a standard microscope objective (finite conjugated 10X Semi-Plan Standard Objective, Edmund Optics). While the length of this lens piece is specific to the lenses used here, due to the modular nature of the DOME it would be trivial to adjust this dimension to suit alternative optics. Positioning both the camera and projector perpendicular to the sample stage results in significant lens flare through which imaging is difficult. To circumnavigate this the projector is angled at 10°, positioning the bright spot created by the light source of the projector out of the camera field of view (FOV).