Fig: Mechanism of action
Patients undergoing abdominal surgery, on the other hand, are at risk for experiencing early postoperative pain. Postoperative patients must be protected from the negative effects of analgesic medicines – particularly opioids – to the greatest extent possible. Dexmeditomidine has been found to improve postoperative outcomes as an opioid-sparing analgesic.
The primary goals of this study were to investigate the analgesic efficacy and opioid sparing effects of perioperative Dexmeditomidine in patients undergoing abdominal surgery, as well as the impact of Dexmeditomidine on postoperative pain.
Several secondary objectives, including the effects of Dexmeditomidine on postoperative nausea and vomiting (PONV), gastrointestinal function, and mobility were investigated, as well as the drug’s adverse effect profile, were also investigated.