Fig: Mechanism of action
Patients undergoing abdominal surgery, on the other hand, are at risk
for experiencing early postoperative pain. Postoperative patients must
be protected from the negative effects of analgesic medicines –
particularly opioids – to the greatest extent possible. Dexmeditomidine
has been found to improve postoperative outcomes as an opioid-sparing
analgesic.
The primary goals of this study were to investigate the analgesic
efficacy and opioid sparing effects of perioperative Dexmeditomidine in
patients undergoing abdominal surgery, as well as the impact of
Dexmeditomidine on postoperative pain.
Several secondary objectives, including the effects of Dexmeditomidine
on postoperative nausea and vomiting (PONV), gastrointestinal function,
and mobility were investigated, as well as the drug’s adverse effect
profile, were also investigated.