Treatment for DIDM in during ALL directed therapy
In view of potential adverse effects of hyperglycaemia, all children on ALL directed therapy who fits into the diagnostic category would need prompt initiation of treatment. Generally, offending drugs are not reduced or stopped, instead treatment of hyperglycaemia to be optimised(40)(3). Considering the heterogeneity of factors that affect the development of DIDM in ALL, treatment strategy should be individualised. Treatment considerations for DIDM in ALL may include non-pharmacologic and pharmacologic measures.