Conclusion
Prompt monitoring for hyperglycemia is suggested for early diagnosis and treatment of DIDM among children with ALL on corticosteroids and L-asparaginase. Elevated fasting (≥126 mg/dl) or post lunch (≥200 mg/dl) POC glucose is the suggested criteria for diagnosis of DIDM. Insulin is the treatment of choice for DIDM, while insulin regimen to be chosen based on the pattern of hyperglycemia. While on insulin frequent blood glucose monitoring and dose titration to achieve target sugar levels (140-180 mg/dl) and watch for hypoglycemia is suggested. Treatment options other than insulin are generally not suggested for DIDM in pediatric ALL setting.
Conflict of Interest : The authors declare no conflict of interest
Funding: None
Acknowledgments: None