Treatment for DIDM in during ALL directed therapy
In view of potential adverse effects of hyperglycaemia, all children on
ALL directed therapy who fits into the diagnostic category would need
prompt initiation of treatment. Generally, offending drugs are not
reduced or stopped, instead treatment of hyperglycaemia to be
optimised(40)(3). Considering the heterogeneity of factors that affect
the development of DIDM in ALL, treatment strategy should be
individualised. Treatment considerations for DIDM in ALL may include
non-pharmacologic and pharmacologic measures.