Non-pharmacologic treatment
Non-pharmacologic treatment such as use of dextrose free fluids and
dietary management should be first thing to be considered as soon as the
diagnosis of DIDM is entertained, unless patient is unstable and/or has
metabolic derangements due to severe hyperglycemia. Dietary changes
should focus on optimizing the amount and type of carbohydrates (avoid
simple sugars and increase proportion of complex carbohydrates), taking
care of the caloric needs of the child to maintain adequate weight
during therapy. Challenges specific to ALL patients i.e., poor appetite,
catabolic state, treatment induced gastritis/gastro esophagitis should
be addressed whenever possible.