FET cycle characteristics and pregnancy outcomes
Table
2 summarises FET cycle characteristics and pregnancy outcomes for the
four PCOS phenotype and control groups. A difference was found for the
presence of a corpus luteum and endometrial thickness between the five
groups (P < 0.001 for both). Women with PCOS phenotype
A showed an increased incidence of biochemical pregnancy, CP and
premature delivery compared to those with PCOS phenotype D and in the
control group (P < 0.001, P = 0.005, P =
0.006, respectively), while the incidence of ectopic pregnancy and LB
were comparable between the five groups (P = 0.596, P =
0.397, respectively). We also found a significantly higher abortion rate
(P = 0.010) and lower ongoing pregnancy rate (P = 0.023)
among PCOS phenotypes A and D compared to control groups.
After adjusting for potential confounders, PCOS phenotypes A and D (vs.
control) were associated with an elevated risk of abortion (adjusted OR,
1.476, 95% CI, 1.077–2.024, P = 0.016; adjusted OR, 1.348, 95%
CI, 1.080–1.682, P = 0.008, respectively). PCOS phenotype A (vs.
control) was not a significant risk factor for a preterm delivery after
adjusting results for potential confounders (P = 0.144;Table 3 ). Potential confounders of abortion (P< 0.05 in univariate logistic regression analysis) included
age, BMI, duration and type of infertility, FBG, the number of retrieved
oocytes and good quality embryos, and the presence or absence of a
corpus luteum. Potential confounders of premature delivery (P< 0.05 in univariate logistic regression analysis) included
SBP, DBP, BMI, type of infertility, To, AMH, AFC and the number of
transferred blastocysts in FET.