5. CNCLUSION
Intussusception in the adult population is often associated with underlying pathology. Considering that adult intussusception is a rare entity with inaccurate medical history and clinical examination. Imaging method evaluations are needed for diagnosis. Primary small bowel DLBCL can present a variety of clinical manifestations, which shows the importance of a highly suspected clinically, which is helpful for rapid diagnosis and subsequent treatment. Thus, learning aim based on this extremely rare case report, we can learn that its clinical manifestations, morphological characteristics, immunophenotypes and molecular biological characteristics are very different and important, which is challenging to preoperative diagnosis. Clinicians and surgeons should keep this in mind in the assessment of patients with intestinal obstruction, and should always be kept in the differential diagnosis of intussusception, especially in the older age or children groups. Emergency surgery is an option to treat severe intussusception. The diagnosis for localized intestinal DLBCL is usually confirmed by histopathology and IHC examination after obtained surgical specimen. Surgery, chemotherapy, radiotherapy and or immunotherapy is a different application of its management, may be in a different combination.